Does metoclopramide improve quality of endoscopy in acute upper gastrointestinal bleeding?.

Phase 4

• Conditions: pper Gastrointestinal Bleeding; Upper Gastrointestinal Bleeding; Oral and Gastrointestinal - Normal oral and gastrointestinal development and function

• Registration Number: ACTRN12605000745640
• Lead Sponsor: Pharmacy department , Southerm Health.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-11-16
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Upper GI bleeding defined as either fresh and bright red or coffee ground haematemesis, Admission within 12 hours of initial clinical signs of bleeding and Written informed consent from patient.

Exclusion Criteria

Previous allergy to metoclopramide, use of Nasogastric tube or gastric lavage, Prior gastrectomy, Pregnancy or lactation, Unable to give informed consent for any reason, Parkinsons disease and other contraindication to use of metoclopramide, Severe renal impairment and Advanced liver disease .

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome for this study is quality of endoscopic examination reported as:<br>a) % empty stomach using objective scores of 0 to 2.[Measured at time of endoscopic procedure by the gastroenterologist];The primary outcome for this study is quality of endoscopic examination to be reported as:<br>b) Ease of visibility of bleeding source, using a 7 point scale from no blood (7) to large amount of blood completely obscuring the view (1).[Measured at time of endoscopic procedure by the gastroenterologist]

Secondary Outcome Measures

Name	Time	Method
The secondary outcomes will be based on analysis of results measured at time of endoscopic procedure and recorded on the case report form by the edoscopist after the procedure. This secondary outcome will be reported as: 1) % of patients with re-scope (due to problems with visualization) 2) Mean Duration of endoscopy (minutes).[]