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Accuracy of Dental Implant Position Robotic Assistance, Dynamic Navigation, or Static Guide?

Not Applicable
Recruiting
Conditions
Dental Implant
Interventions
Device: Robotic system
Device: Static guide
Device: Dynamic navigation
Registration Number
NCT05892406
Lead Sponsor
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Brief Summary

For free hand dental implant placement, a key difficulty is to accurately control the position. Improving precision of dental implant placement is considered important for safety and efficacy of tooth replacement with dental implants. There are 3 available methods to improve implant position according to a digitally constructed prosthetically guided plan: the use of a 3D printed static guide, the use of a dynamic navigation system or the use of a robotic system. The goal of this randomized controlled trial is to compare the positional implant accuracy, the surgical time, and patient satisfaction among three methods of digital guidance: the use of a 3D printed static guide, dynamic navigation, and robotic assisted surgery. Patients requiring single tooth replacement with a dental implant will be digitally planned using a CBCT and an intraoral digital scan. Subjects will be randomized to one of the three treatment modalities based on the plan. The accuracy of placement will be assessed evaluating the difference between the planned and the actual position using a follow-up scan taken at the end of the surgery. Subjects will be followed up for one year to assess both patient reported and professional outcomes.

Detailed Description

For free hand dental implant placement, a key difficulty is to accurately control the position. Improving precision of dental implant placement is considered important for safety and efficacy of tooth replacement with dental implants. There are 3 available methods to improve implant position according to a digitally constructed prosthetically guided plan: the use of a 3D printed static guide, the use of a dynamic navigation system or the use of a robotic system. The goal of this randomized controlled trial is to compare the positional implant accuracy, the surgical time, and patient satisfaction among three methods of digital guidance: the use of a 3D printed static guide, dynamic navigation, and robotic assisted surgery. Patients requiring single tooth replacement with a dental implant will be digitally planned using a CBCT and an intraoral digital scan. Subjects will be randomized to one of the three treatment modalities based on the plan. The accuracy of placement will be assessed evaluating the difference between the planned and the actual position using a follow-up scan taken at the end of the surgery. Platform deviation will be measured digitally. Subjects will be followed up for one year to assess both patient reported and professional outcomes and associate them with the precision of implant position.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
45
Inclusion Criteria
  • Patient with a single missing tooth, with sufficient bone volume and keratinized tissue at edentulous site, willing to comply with research appointments/schedule.
Exclusion Criteria
  • Pregnancy or intention to become pregnant at any point during the study duration; with any systematic diseases/conditions that are contradictions to dental implant treatment; inability or unwillingness of individual to give written informed consent; inability of follow-up according to the protocol.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Robotic systemRobotic systemProsthetically guided Implant placement utilising robotic surgery based on a digital plan
Static guideStatic guideProsthetically guided Implant placement utilising a 3D printed static guide based on a digital plan
Dynamic navigationDynamic navigationProsthetically guided Implant placement utilising a dynamic navigation system based on a digital plan
Primary Outcome Measures
NameTimeMethod
Peri-implant soft tissue health12 month follow-up

Defined according to the peri-implant health case definition by Berglundh et al 2017 and the ID-COSM international consensus conference

Implant positional accuracyImmediately after surgery

Implant accuracy will be measured as discrepancy between the digital plan and t actual position of the implant.

Secondary Outcome Measures
NameTimeMethod
Cytokine concentrations in PISF12-months follow-up after delivery of crown

Cytokine concentration in peri-implant sulcus fluid assesed by MULTIPLEX ELISA of IL-1, TNFa, IL-6 with lower concentrations representing less inflammation.

Surgery timeintraoperative

Time needed for surgery procedure will be recorded from anaesthesia to connection of cover screw/healing abutment.

Pain perception7 days after surgery

Patient pain perception after surgery will be recorded using visual analogue scale (VAS with range from 0 to 10 with 10 being the highest possible pain experience) .

Patient preferenceImmediately after surgery

Assessed using a visual analogue scale (VAS, 100 mm, with 0=least desirable option and 100 = most desirable option.

Surgeon preferenceImmediately after surgery

Assessed using a visual analogue scale (VAS, 100 mm, with 0=least desirable option and 100 = most desirable option.

Esthetics of the restoration12-months follow-up after delivery of crown

Assessed using the PES-WES scale as reported by Belser et al. with 0 being the worst and 14 the best value in the scale

Submarginal microbiome12-months follow-up after delivery of crown

16S assessment of microbiome diversity (Shannon index) with greater diversity representing a more stable microbiome

Trial Locations

Locations (2)

Shanghai Perio-Implant Innovation Center

🇨🇳

Shanghai, Shanghai, China

Department of Oral and Maxillofacial Implantology

🇨🇳

Shanghai, Shanghai, China

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