Identifying Molecular Drivers of Cancer
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Cancer
- Sponsor
- Avera McKennan Hospital & University Health Center
- Enrollment
- 579
- Locations
- 1
- Primary Endpoint
- Genetic profiling
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The primary aim of this study is to identify drivers of cancer by performing comprehensive genetic, proteomic, and metabolomic characterization of patient samples as a basis for understanding the underlying cause of disease.
Detailed Description
This study involves looking at the DNA, RNA, proteins, and metabolites in blood and tissue samples collected from subjects and linking them to their health information. By doing so, researchers hope to discover the underlying molecular causes of human diseases with the hope that this information can be used for the development of diagnostic tests and more effective treatments.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients diagnoses with cancer but healthy enough to undergo a biopsy procedure
- •Between the ages of 18 and 100
Exclusion Criteria
- •Patients who are pregnant
Outcomes
Primary Outcomes
Genetic profiling
Time Frame: Up to 15 years
To determine genetic changes associated with the development and growth of human disease. This should lead to better ways to detect, prevent, and treat a wide variety of human health conditions, including cancer.