The Effect of Liposuction on Menses: a Retrospective Study

Early Phase 1

Completed

• Conditions: Menstrual Irregularity
• Interventions: Procedure: Liposuction; Procedure: Other plastic surgery

• Registration Number: NCT04985591
• Lead Sponsor: Shanghai Jiao Tong University School of Medicine

Brief Summary

The prevalence of obesity nearly tripled from 1975 to 2021, resulting in liposuction, as an effective shaping method, to be performed more frequently. Liposuction is a surgical procedure that uses a specialized instrument to suck fat fragments in the subcutaneous fat layer through a small incision. Analyzing a large sample sizes of patients who had liposuction, we found that some female patients underwent menstrual irregularity after liposuction. In 2004, Carolyn et al. reported several cases in which there was a connection between liposuction and an early onset of menses. Further studies showed that an early onset of menses may be related to the volume of adipose tissue extracted, the amount of anesthesia given, the area of liposuction, and body weight. However, the sample of that study was small, as there were only 17 cases included in the statistical model, and there are few articles in which the impact of liposuction on menses has been studied. To better understand whether menstrual irregularity will occur after liposuction, patients with postmenopausal or preoperative menstrual irregularity were excluded, leaving a sample of 518 female patients to be reviewed. A better understanding of the impact of liposuction on menses may help clinical doctors predict the underlying risk of menstrual irregularity after liposuction and identify individuals at higher risk. The findings may contribute to further understanding of menstrual irregularity.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-06-14
• Primary Completion: 2021-03-12
• Study Completion: 2021-03-12
• Status Verified: 2021-07
• Study First Submitted: 2021-07-22
• Study First Submitted QC: 2021-07-22
• Last Update Submitted: 2021-07-22
• Study First Posted: 2021-08-02
• Last Update Posted: 2021-08-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 516

Inclusion Criteria

patients who were in 18-55 and have a regular menses -

Exclusion Criteria

Patients who were younger than 18 years old or older than 55 years old, who were in the perimenopausal or postmenopausal stage or who had menstrual irregularity before plastic surgery were excluded from both groups.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
liposuction group	Liposuction	-
Other plastic surgery group	Other plastic surgery	-

Primary Outcome Measures

Name	Time	Method
menstrual irregularity	three months	to detect any change in the menses during the following 3 months, post surgery