Correlation testing of toxin-producing Clostridioides difficile toxin B detection reagents in stool samples.
Not Applicable
Recruiting
- Conditions
- Infectious diseases
- Registration Number
- JPRN-jRCT1032230481
- Lead Sponsor
- Suzuki Hiromichi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 700
Inclusion Criteria
Existing residual stool samples with a Bristol stool scale of 5 or higher were collected for C. difficile testing.
Exclusion Criteria
1) In the event that there were no residual samples to carry out this study.
2) If the toxin gene in the stool could not be detected within 5 days after collection
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlative evaluation of the existing method for toxin-producing C.difficile toxin B detection in stool samples using a dedicated reagent for the GeneLEAD series, a fully automated gene analysis instrument.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms enable toxin B detection reagents to identify Clostridioides difficile in stool samples?
How does JPRN-jRCT1032230481 compare to standard GDH or toxin A/B immunoassays in C. difficile diagnostic accuracy?
Which stool biomarkers correlate with toxin B levels to predict C. difficile infection severity or recurrence risk?
What adverse events are associated with false-positive toxin B detection in C. difficile testing and mitigation strategies?
What are the current FDA-approved or investigational compounds targeting C. difficile toxins for improved diagnostic or therapeutic outcomes?