NCT02167503
Unknown
Not Applicable
A Retrospective-prospective Observational Study to Evaluate the Effect of Anti-viral Treatment on the Long-term Outcome in Patients With Chronic Hepatitis B (SEARCH-B Study)
ConditionsChronic Hepatitis B
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Hepatitis B
- Sponsor
- Nanfang Hospital, Southern Medical University
- Enrollment
- 10000
- Locations
- 14
- Primary Endpoint
- Cumulative rates of hepatocellular carcinoma
- Last Updated
- 11 years ago
Overview
Brief Summary
The study was conducted to evaluate the effect of anti-viral treatment on long-term outcome on patients with chronic hepatitis B.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Male or female, aged over 30 (inclusive) years of old
- •Patients has a history of diagnosis of chronic hepatitis B (ie. HBsAg positive for more than 6 months)
- •For patients with HBsAg positive, patients should be undergoing anti-viral treatment
- •For patients with HBsAg negative, a documented evidence of previous anti-viral treatment should be provided.
- •Life expectancy is more than 1 year
- •Good treatment compliance.
Exclusion Criteria
- •Patients has a history of diagnosis of hepatocellular carcinoma
- •Patients with Child Pugh C
- •Coinfected with HCV, HDV and HIV
- •Suffering from other serious disease
- •Taking part in other clinical trial
Outcomes
Primary Outcomes
Cumulative rates of hepatocellular carcinoma
Time Frame: Year 5
Study Sites (14)
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