Determination of the impact of Posterior Nasal Nerve Neurectomy in patients of Allergic Rhinitis intractable to medical management
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 90
- Locations
- 1
- Primary Endpoint
- Improvement in the quality of life of patients of Allergic Rhinitis intractable to medical management, post Posterior nasal nerve neurectomy by pre operative and post operative comparison of the SNOT 22 score and Total nasal symptom score
Study Overview
Brief Summary
Assessment of the impact on Posterior Nasal Nerve Neurectomy in patients of Allergic Rhinitis intractable to medical management of > 1 month by comparing preoperative and post operative symptom scores and to assess the impact of the surgery on improving the quality of life of patients of Allergic Rhinitis. The study will assess the effect of Posterior Nasal Nerve Neurectomy on specific symptoms of Allergic Rhintis as well and compare the improvement in symptoms with improvement after other procedures such as Inferior Turbinoplasty with or without septal correction.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18.00 Year(s) to 50.00 Year(s) (—)
Inclusion Criteria
- •AGE – 18 to 50 years of age
- •Gender : Male and Female
- •Cases of Allergic Rhinitis: Patients with moderate/severe Persistent Allergic Rhinitis as per ARIA guidelines (symptoms for more than 4 days per week AND for more than 4 consecutive weeks per year; with one or more of the following : abnormal sleep, impairment of daily activities, sport, leisure, Problems caused at school or work, Troublesome symptoms) having 2 or more typical symptoms of Allergic Rhinitis.
- •anterior or posterior rhinorrhoea, sneezing, nasal blockage and/or itching of the nose – who have shown no significant improvement in symptoms after Medical Management ( with Oral Antihistamines and Steroid Nasal Sprays for more than or equal to 1 month)
- •Allergic Skin Prick Test – Patient sensitized to 1 or more allergens.
- •Associated Anatomical variations such as Septal Deviation, Hypertrophied Turbinates.
- •Bronchial Asthma in addition to Allergic Rhinitis.
Exclusion Criteria
- •Congenital Anomalies of the nose
- •Patients post Sinonasal surgeries.
- •Sinonasal polyposis
- •Sinonasal malignancies
- •Previous radiation to Head and Neck
- •Head and neck trauma
- •Associated Syndromic conditions such as Kartagener’s syndrome, Young syndrome.
- •Bleeding Diathesis.
Outcomes
Primary Outcomes
Improvement in the quality of life of patients of Allergic Rhinitis intractable to medical management, post Posterior nasal nerve neurectomy by pre operative and post operative comparison of the SNOT 22 score and Total nasal symptom score
Time Frame: 1 week, 1 month and 3 months post Posterior Nasal Nerve Neurectomy
Secondary Outcomes
- 1. Comparing the effectiveness of Posterior Nasal Neurectomy and Inferior Turbinoplasty and a combination of the two procedures (with or without septal correction) in reduction of symptoms of Allergic Rhinitis.(2. Assessment of the effect of Posterior Nasal Neurectomy on the specific symptoms of Allergic Rhinitis.)
Investigators
Sneha Madhavarapu
Kasturba Medical College, MAHE, Manipal