CTRI/2024/07/071439尚未招募不适用
Evaluating opportunities for antibiotic de-escalation and its clinical impact in an intensive care unit : A prospective observational study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 206
- 试验地点
- 1
- 主要终点
- prevalence of antibiotic de-escalation.
研究概览
简要总结
Among critical care patients, apart from the patient factors, there is lack of definition
of antimicrobial de-escalation which fits all the clinical scenarios. Additionally, there is no
consensus available for hierarchy of antimicrobials 2. In our study the aim is to evaluate the
scope available for antimicrobial de-escalation, and to determine the impact of the same in
critically ill patients of a tertiary care medical ICU.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with suspected infection/sepsis, started on empirical antibiotic therapy for more than or equal to 24 hours.
- •Patients who will are admitted in ICU for at least 5 days or more.
排除标准
- •Patients on antibiotics as definitive therapy as per culture sensitivity.
结局指标
主要结局
prevalence of antibiotic de-escalation.
时间窗: during icu stay
次要结局
- length of ICU(stay, mortality among the study population, new onset organ failure, emergence of resistance)
研究者
Dr Harsha Vardhini C P
St Johns Medical College Hospital
研究点 (1)
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