Investigation of the Relationship Between Arterial Stiffness and Pulmonary and Extrapulmonary Features in Patients With Ankylosing Spondylitis
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Arterial stiffness
研究概览
简要总结
The aim of this study was to investigate the relationship between arterial stiffness and pulmonary and extrapulmonary features in patients with ankylosing spondylitis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of ankylosing spondylitis according to ASAS diagnostic criteria
- •Being aged 18-65
- •Stable medication use for at least 3 months
- •Voluntary participation in the study
排除标准
- •Having uncontrolled cardiopulmonary disease
- •Being pregnant
- •Having undergone recent surgery
- •Presence of malignancy
- •Failure to perform to assessments
结局指标
主要结局
Arterial stiffness
时间窗: 1st day
It will be evaluated with brachial pulse waves.
Respiratory muscle strength
时间窗: 1st day
Maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) will be measured using a portable mouth pressure device.
Respiratory muscle endurance
时间窗: 1st day
This will be evaluated with increased workload testing.
Exercise capacity
时间窗: 1st day
Exercise capacity will be assessed with 6 minute walk test.
Peripheral muscle strength
时间窗: 1st day
Hand grip strength will be assessed with a grip dynamometer.
Muscle function
时间窗: 1st day
It will be evaluated with one-minute sit to stand test
次要结局
- Physical activity(1st day)
- Forced vital capacity(1st day)
- Forced expiratory volume in one second(1st day)
- Forced expiratory volume in one second/forced vital capacity ratio(1st day)
- Peak expiratory flow(1st day)
- Forced mid-expiratory flow(1st day)
研究者
Merve Firat
Assistant Professor
Kirsehir Ahi Evran Universitesi