NCT00707525已完成4 期
Incidence of EmbyoO Aneuploidies in Natural Versus Stimulated Cycles in the Same Women.
Instituto Valenciano de Infertilidad, IVI VALENCIA2 个研究点 分布在 1 个国家开始时间: 2008年2月1日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 试验地点
- 2
- 主要终点
- Embryo aneuploidies
研究概览
简要总结
There is a considerable concern about the effects of controlled ovarian hyperstimulation (COH) for In Vitro Fertilization- Embryo Transfer (IVF-ET) on embryo quality and on the incidence of chromosomal abnormalities in oocytes and embryos.
The main question remaining is if COH may increase the aneuploidies rate in young and healthy women. Therefore, the primary endpoint of the present study is to analyse the incidence of chromosomal abnormalities in this group of patients (oocyte donors), either in oocytes obtained after a natural cycle or in those retrieved after a COH cycle. To get rid of the male factor influence, donated sperm will be used.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Donor Inclusion Criteria:
- •18 to 35 years old.
- •BMI: 18-25Kg/m2
- •Regular menstrual cycles
- •Normal kariotype
- •No previous controlled ovarian hyperstimulation (COH) treatments.
排除标准
- •Endometriosis
- •Policystic ovarian syndrome
- •Recurrent miscarriages.
- •Recipient Inclusion Criteria
- •Aged until 45 years old
- •No systemic diseases
- •Following egg and sperm donation treatment.
- •Recipient exclusion criteria:
- •Uterine disease (polyps, myomas, mullerian defects)
- •Recurrent miscarriages.
结局指标
主要结局
Embryo aneuploidies
时间窗: 2 cycles
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
相似试验
Unknown
4 期
Comparing Coasting by Withholding GnRH Agonist With GnRH AntagonistIn Vitro FertilizationNCT01347268Shin Kong Wu Ho-Su Memorial Hospital120
Unknown
不适用
CuMulativE Live bIrth Rate of Patients at High Risk of OHSS After Freeze-all Embryos at Cleavage or blAstocyst StageInfertilityNCT03817060Université Libre de Bruxelles128
已完成
不适用
Effects of Controlled Ovarian Hyperstimulation (COH) With Letrozole and GonadotropinBreast CancerInfertilityNCT01403688University of Kansas9
已完成
不适用
Controlled Ovarian Stimulation by HP-hMG for IVF / ICSI Cycles: Study on Ovarian Hyper Stimulation Syndrome in a Cohort of Women From 18 to 36 Years Old.Ovarian Hyperstimulation Syndrome (OHSS)NCT01703728Ferring Pharmaceuticals455
已完成
4 期
NATural Ovarian StimulationInfertilityNCT02892942Assistance Publique - Hôpitaux de Paris129