ISRCTN18225522
Suspended
未知
A pilot study to compare the response of psoriasis to narrow-band UVB phototherapy in the morning and afternoon (Psoriasis and the Circadian Timing System [Version 1])
ewcastle upon Tyne Hospitals NHS Foundation Trust0 sites20 target enrollmentApril 23, 2020
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Psoriasis
- Sponsor
- ewcastle upon Tyne Hospitals NHS Foundation Trust
- Enrollment
- 20
- Status
- Suspended
- Last Updated
- 5 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. At least 18 years of age
- •2\. Able to speak English
- •3\. Able to provide written informed consent
- •4\. Have chronic plaque psoriasis
- •5\. Prescribed NbUVB phototherapy
- •6\. Able and willing to attend the phototherapy department regularly
Exclusion Criteria
- •1\. Able to control their psoriasis or already controlled by topical therapy
- •2\. Pregnant
- •3\. Significant sun exposure, sun\-bed use or previous NbUVB within the last month or be planning significant sun exposure or sun\-bed use in the next month
- •4\. Previously taken, in the last three months any of the following: methotrexate, azathioprine, ciclosporin, biological therapy or systemic steroids for treatment of psoriasis
- •5\. Previously taken, in the last month, any oral photosensitising medications, including: thiazide diuretics, antibiotics such as tetracyclines and quinolones, non\-steroidal anti\-inflammatory drugs, phenothiazines, retinoids, sulphonylureas, quinine and St John’s Wort
- •6\. Also suffer from diseases where phototherapeutic treatment is contraindicated: xeroderma pigmentosum, lupus erythematosus
- •7\. Work night\-shifts
- •8\. Diagnosed circadian rhythm disorder
Outcomes
Primary Outcomes
Not specified
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