Effectiveness of Chai-shi-Tui-Re (CHASE) granules for influenza A: a randomized controlled trial

Phase 4

• Conditions: Influenza A

• Registration Number: ITMCTR1900002866
• Lead Sponsor: Guangdong Provincial Hospital of Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Defined according to influenza A diagnostic criteria;
2. TCM syndrome differentiation is wind-heat invading defensive qi or heat-toxicity attacking lung;
3. Onset within 48 hours;
4. Temperature equal or more then 38.0? within 24 hours;
5. Complete blood count shows normal or lower white blood cell count;
6. Aged 18 to 65 years;
7. Patients signed informed consent.

Exclusion Criteria

1. Chest imaging shows that there is a tracheobronchitis, lung infection or active lung tuberculosis;
2. Those with a history of lung cancer, pneumoconiosis, lung abscess, chronic obstructive pulmonary disease and pulmonary heart diseases;
3. Patients with severe primary diseases such as cardiovascular, renal, liver, hematopoiesis, brain, digestive system and psychiatric and malignant tumors;
4. Those who injected influenza vaccination in the past 12 months;
5. Those who have used antivirals, antipyretics, analgesics or traditional Chinese medicine in the past 24 hours;
6. Those who are using systemic glucocorticoids or immunosuppressants;
7. Pregnancy or breast-feeding women;
8. Allergic constitution or those who are allergic to multiple drugs.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Defervescence time;

Secondary Outcome Measures

Name	Time	Method
Defervescence rate;Utilization rate of analgesic-antipyretic;Incidence of flu complications;symptom score;Negative rate of viral nucleic acid;