Effectiveness of Internet-based Depression Treatment (EVIDENT) in Severe Depression

University of Luebeck4 sites in 2 countries163 target enrollmentFebruary 2013

ConditionsSevere Depressive Symptoms

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Severe Depressive Symptoms
Sponsor: University of Luebeck
Enrollment: 163
Locations: 4
Primary Endpoint: Patient Health Questionnaire - 9 items (PHQ-9)
Status: Completed
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Online self-help is an innovative way of providing self-help. The investigators want to study the effect of an interactive online self-help-program (Deprexis) in the treatment of severe depressive symptoms. Participants will be randomised to either twelve weeks of online-self help or a waiting-list control. Symptoms of depression and other aspects will be assessed over a six months period. The investigators hypothesise that online self-help is superior to the control condition in alleviating depressive symptoms and preventing full blown depression.

Registry

clinicaltrials.gov

Start Date

February 2013

End Date

May 2014

Last Updated

10 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University of Luebeck

Responsible Party

Principal Investigator

Philipp Klein

Dr. med.

University of Luebeck

Eligibility Criteria

Inclusion Criteria

•Age between 18 and 65, ability to read German, willingness to participate in a telephone diagnostic interview, achieving a score of at least 15 on the PHQ-9 in an initial screening, and providing written informed consent

Exclusion Criteria

•Lifetime diagnosis of schizophrenia or bipolar disorder (as determined by a telephone diagnostic interview) or current suicidality (as determined in a telephone interview)

Outcomes

Primary Outcomes

Patient Health Questionnaire - 9 items (PHQ-9)

Time Frame: Change from Baseline to post (3mths).

Secondary Outcomes

Quick Inventory of Depressive Symptoms - Self-Rreport (QIDS-SR16)(Baseline, post (3 mths), follow-up (6 mths))
Generalized Anxiety Disorder - 7 (GAD-7)(Baseline, post (3 mths), follow-up (6 mths))
Patient Health Questionnaire - 15 items (PHQ-15)(Baseline, post (3 mths), follow-up (6 mths))
Short Form Health Survey - 12 (SF-12)(Baseline, post (3 mths), follow-up (6 mths))