Effects of consumption of the test food on the oral environment in healthy subjects
- Conditions
- Healthy Japanese subjects
- Registration Number
- JPRN-UMIN000048609
- Lead Sponsor
- ORTHOMEDICO Inc.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 34
Not provided
1. Subjects who are undergoing medical treatment or have a medical history of malignant tumor, heart failure, and myocardial infarction 2. Subjects who have a pacemaker or an implantable cardioverter defibrillator (ICD) 3. Subjects who currently undergoing treatment for any of the following chronic disease: cardiac arrhythmia, liver disorder, kidney disorder, cerebrovascular disorder, rheumatism, diabetes mellitus, dyslipidemia, hypertension, or any other chronic diseases 4. Subjects who use or take "Foods for Specified Health Uses," or "Foods with Functional Claims" in daily 5. Subjects who are currently taking medications (including herbal medicines) and supplements 6. Subjects who are allergic to medicines and/or the test food related products 7. Subjects who are pregnant, lactation, or planning to become pregnant during this trial 8. Subjects who suffer from COVID-19 9. Subjects who have been enrolled in other clinical trials within the last 28 days before the agreement to participate in this trial or plan to participate another trial during this trial 10. Subjects who are judged as ineligible to participate in this study by the physician 11. Subjects who use artificial tooth, post crowns, dentures, implants or bridges 12. Subjects who regularly use gargle medicine or mouthwash 13. Subjects who have a medical history or current history of Sjogren's syndrome, or who are suspected it 14. Subjects who have diseases associated with salivary gland such as dry mouse and salivary stone disease 15. Subjects who are undergoing medical treatment for periodontosis or dental caries 16. Subjects who are dental treatment or have dental diseases 17. Subjects who are smokers, or started smoking cessation within one year before the agreement to participate in this trial
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. The measurement value of halitosis {brilliant breath (B/B) value in B/B checker}
- Secondary Outcome Measures
Name Time Method 1. Subjective symptom measured by visual analogue scale (an original questionnaire) 2. The volume of saliva