NCT02079597已完成不适用
Prospective Study to Analyze Ninjurin-1 and Its Soluble Part During Systemic Inflammation
Dr. Patrick Meybohm, M.D.1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2014年2月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Ninj1 expression on blood leukocytes
研究概览
简要总结
- With the underlying study the investigators address the question if Ninjurin-1 (Ninj1) expression is altered in patients with systemic inflammatory response syndrome (SIRS) in comparison to healthy volunteers.
- The adhesion molecule Ninj1 is induced following nerve injury where it contributes to nerve generation. Besides it is described to facilitate leukocyte migration especially in the nervous system.
- The investigators hypothesize that Ninj1 expression is increased in SIRS patients, which will fortify its impact during inflammation and the transferability from bench to bedside.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age > 18 years
- •cardiac surgery patients
排除标准
- •included in an interventional study
- •Preoperative Infection (e.g. Endocarditis)
结局指标
主要结局
Ninj1 expression on blood leukocytes
时间窗: one day post surgery
次要结局
- grade of systemic inflammation(one day post surgery)
研究者
Dr. Patrick Meybohm, M.D.
PD Dr. Patrick Meybohm, M.D.
Johann Wolfgang Goethe University Hospital
研究点 (1)
Loading locations...
相似试验
已完成
不适用
A prospective study of the effects of Ninjin'yoeito on anemia and depressive symptoms in postpartum womePostpartum anemiaJPRN-UMIN000044116Fukuda Hospital1,000
已完成
2 期
An Exploratory Study of Nesiritide in Participants With Acute Heart FailureHeart Failure, CongestiveNCT00490724Janssen Pharmaceutical K.K.67
已完成
不适用
Correlation Between the Analgesic Effect of Fentanyl Transdermal Patches and Nutritional Status in Cancer Pain PatientsNutrition DisordersCancer PainNCT06369961Chongqing University Cancer Hospital151
尚未招募
1 期
Treatment of Nidranasha by Jatamansi Churna and Nirgundi Taila PadabhyangaCTRI/2022/11/047445Manasi Pradhan
已完成
1 期
A Study to Test Whether Nintedanib Influences the Components of Birth-control Pills in Women With Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD)Scleroderma, SystemicNCT03675581Boehringer Ingelheim17