Effects of Intrapulmonary Percussive Ventilator on Respiratory Function: an Experiment in Healthy Volunteers
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Airway Clearance Impairment
- Sponsor
- Shanghai 10th People's Hospital
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Pulmonary function test
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The goal of this clinical trial is to prove the benefit of intrapulmonary percussive ventilator in healthy volunteers. The main questions are:
- How can intrapulmonary percussive improve lung function？
- What is the subjective feeling through intrapulmonary percussive?
Participants will be undergoing treatment of intrapulmonary percussive. Then they will be assessed for lung function and EIT before and after intrapulmonary percussive.
Investigators
Sheng Wang MD PhD
MD PhD
Shanghai 10th People's Hospital
Eligibility Criteria
Inclusion Criteria
- •No respiratory system, heart disease
- •Well cooperate with the MateNeb
Exclusion Criteria
- •No respiratory illness such as influenza, pneumonia, asthma, bronchitis within the last month
- •Couldn't finish three times pulmonary function test
Outcomes
Primary Outcomes
Pulmonary function test
Time Frame: through study completion, an average one hour
This test can assess the volunteer's lung ventilation and diffusion function.For example the max vital capacity (VCMAX),Forced vital capacity(FVC),Forced expiratory volume in one second(FEV1),functional residual capacity(FRC-SB),diffusion capacity of lung for carbon monoxide(DLCO) and so on.
Electrical Impedance Tomography of Pulmonary(EIT)
Time Frame: through study completion, an average one hour
EIT is a relatively advanced non-invasive monitoring technique for the lung function. This technology uses a strap attached to the chest to monitor electrical at 16 locations. The Ventilation in each area resistance of the lung is quantified according to the electrical resistance
Secondary Outcomes
- The safety and comfort(The treatment was scored once after the participants completed both low and high frequency intrapulmonary percussive.Up to one week.)