Evaluation of Preventive Effect of Intravenous Trans Sodium Crocetinate on Contrast-Induced Nephropathy
Phase 2
Recruiting
- Conditions
- Certain current complications following acute myocardial infarction.Certain current complications following ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction (within the 28 day period)
- Registration Number
- IRCT20081019001369N8
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 152
Inclusion Criteria
Candidates for outpatient angioplasty
Exclusion Criteria
The presence of ESRD requires dialysis before angiography
Presence of underlying diseases leading to acute renal failure regardless of contrast-induced acute renal failure
Existence of active tumor
History of exposure to intravenous contrast agents in the last 14 days for other reasons
Existence of heart failure or cardiogenic shock
Taking drugs interacting kidney function
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effect of TSC on the occurrence of acute kidney injury. Timepoint: during 5 days. Method of measurement: mehran score.
- Secondary Outcome Measures
Name Time Method Effect of TSC administration on creatinine clearance level. Timepoint: days 0 , 1 , 2 ,5. Method of measurement: laboratory evaluation.;Effect of TSC administration on serum creatinine and BUN level. Timepoint: days 0 , 1 , 2 ,5. Method of measurement: laboratory evaluation.;Effect of TSC administration on cystatin C level. Timepoint: days 0 , 1 , 2. Method of measurement: laboratory evaluation.;Effect of TSC administration on hs-CRP level. Timepoint: days 0 , 5. Method of measurement: laboratory evaluation.;Effect of TSC administration on 24hours urine analysis test. Timepoint: days 0 , 1 , 2 ,5. Method of measurement: laboratory evaluation.;Effect of TSC administration on mehran score. Timepoint: days 0 , 5. Method of measurement: laboratory evaluation.;Effect of TSC administration on MDA test. Timepoint: days 0 , 5. Method of measurement: laboratory evaluation.