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临床试验/NL-OMON33825
NL-OMON33825尚未招募4 期

Impulsivity, a risk factor in relapse to substance use disorder: investigating neural substrates before and after pharmacological challenges. - Impulsivity in addiction

Academisch Medisch Centrum0 个研究点目标入组 108 人开始时间: 待定最近更新:
适应症

试验速览

阶段
4 期
状态
尚未招募
入组人数
108

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • 1) 18-60 years old, male
  • 2) Current DSM-IV diagnosis of cocaine dependence or alcohol dependence, but recently detoxified and abstinent
  • 3) Control group does not have any history of addictive behaviors
  • 4) Able to sign informed consent and to comply with all study procedures

排除标准

  • 1) Currently dependent on cocaine for the alcoholgroup
  • 2) Currently dependent on alcohol for the cocaine group
  • 3) Severe neurological or psychiatric disorders (e.g. major depressive disorder, psychosis, bipolar illness, dementia, or any other diseases that require psychotropic medications)
  • 4) Serious medical illness
  • 5) Known hypersensitivity or allergy to N-acetylcysteine or modafinil, or receiving chronic therapy with medication that could interact adversely with one of the medications under study (antibiotics for example), within 30 days prior to randomization, history of peptic ulceration, asthma.
  • 6) Estimated IQ lower than 85
  • 7) Dutch not as his/her primary language

研究者

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