Effect of Systemic Ropivacaine on Hyperalgesia, Flare Reaction and Peripheral Nerve Excitability

Phase 4

Completed

• Conditions: Healthy Volunteers

• Registration Number: NCT00900913
• Lead Sponsor: University of Zurich

Brief Summary

The purpose of this study is to compare the effect of intravenous ropivacaine and lidocaine on the receptive field of primary sensory afferents and their influence on the vascular bed.

\*Trial with medicinal product

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2008-10-21
• Study First Submitted QC: 2009-05-12
• Study First Posted: 2009-05-13
• Study Start: 2010-01
• Primary Completion: 2011-05
• Study Completion: 2011-07
• Status Verified: 2011-08
• Last Update Submitted: 2011-08-05
• Last Update Posted: 2011-08-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 34

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Aera of flare reaction (cm2), area of primary and secondary hyperalgesia (cm2)	1 year

Trial Locations

Locations (1)

Clinical Trial Center; 🇨🇭 Zurich, Switzerland