Comparison of the Effects of Quadratus Lumborum Block 2 and 3 (QLB 2 and QLB 3) on Post-operative Analgesia in Cesarean Section Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Opioid consumption in the first 24 hours after surgery
研究概览
简要总结
This study evaluates the post-operative analgesic effects of quadratus lomborum block 2 and 3 (QLB 2, 3) in patients having cesarean section with spinal anesthesia. Spinal anesthesia will be performed to all patients for the surgery.
详细描述
In this study, patients are divided into two groups. After the spinal anesthesia is performed and cesarean section surgery is over; QLB 2 block will be performed to patients in Group A ; while QLB 3 block will be performed to patients in Group B.
In addition, patient controlled analgesia (PCA) will be used in the first 24 hours postoperatively.
Group A - Patients in group A will have QLB 2 block after the surgery. In addition, patient controlled analgesia (PCA) will be used in the first 24 hours postoperatively.
Group B - Patients in group B will have QLB 3 block after the surgery. In addition, patient controlled analgesia (PCA) will be used in the first 24 hours postoperatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
盲法说明
The anesthesia doctor who will perform the interfascial plane block (QLB 2, 3) will be informed with a sealed envelope by an independent assistant outside the study, and the patient will not know which block is performed.
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Being pregnant for at least 37 weeks
- •Planning an elective cesarean operation
- •Being between the ages of 18-45
排除标准
- •ASA 3-4 patients with comorbitidies (Serious renal, cardiac, hepatic disease)
- •Being operated with general anesthesia
- •Obesity (> 100 kg, BMI> 35 kg / m2)
- •Contraindication of regional anesthesia (quagulopathy, abnormal INR, thrombocytopenia, infection at the injection site)
- •Hypersensitivity to local anesthetics or a history of allergy
- •Patients with a history of opioid use longer than four weeks
- •Patients with psychiatric disorders
- •Patients with anatomic deformity
- •Patients who do not want to participate
结局指标
主要结局
Opioid consumption in the first 24 hours after surgery
时间窗: 1 day
Morphine consumption in the first 24 hours will be counted by IV patient controlled analgesia device (PCA). Patients will be able to request opioids via PCA device when the nrs score is above 4.
次要结局
- Post-operative acute pain(1 day)
研究者
Caner Genç
Medical Doctor
Ondokuz Mayıs University