Ability of a New PPV Smartphone Application to Predict Fluid Responsiveness in Cardiac Surgical Patients in the ICU
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- PPV measure
研究概览
简要总结
The goal of this study is to assess the ability of a new smartphone PPV app to predict fluid responsiveness in cardiac surgical patients in the Intensive care unit (in the postoperative period)
详细描述
Pulse pressure variation (PPV) remains a good predictor of fluid responsiveness in the ICU in ventilated and sedated patients. However, PPV can be time-consuming to calculate (manual determination), is not always displayed on monitoring screens nor reliable through visual assessment and needs additional often costly devices to be displayed. A new Android application (Captesia) automatically calculates the PPV utilizing a digital photograph of the arterial waveform from the monitor. The application determines the PPV by selecting peaks and troughs of the arterial curve.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adults patients ( >18 years)
- •Patients scheduled for cardiac surgery
- •equipped with a femoral arterial catheter and the PICCO device
排除标准
- •Atrial fibrillation
- •severe cardiac dysfunction
研究组 & 干预措施
group/cohort
operated patients from cardiac surgery. Once they arrived in the ICU, we will measure PPV with the capstesia and the PICCO device at baseline, and after a volume expansion of 500 ml of crystalloid.
干预措施: PPV from the capstesia (Other)
结局指标
主要结局
PPV measure
时间窗: 1 minute after the end of volume expansion
PPV before with after 2 maneuvers which modify PPV (increase PEEP level and mini-fluid challenge)
PPV measure
时间窗: baseline
PPV before with after 2 maneuvers which modify PPV (increase PEEP level and mini-fluid challenge)
次要结局
未报告次要终点
研究者
Alexandre Joosten, MD PhD
Principal Investigator
Erasme University Hospital