A Comparative Study of GPI's DBS and Pallidotomy in the Treatment of Meige Syndrome
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Symptom
研究概览
简要总结
In this study, we will compare the degree of postoperative symptom improvement, postoperative complication rate, postoperative quality of life improvement degree of patients with Meige syndrome undergoing pallidotomy (unilateral globus palliotomy) and deep brain stimulation (unilateral globus pallidus) ,in order to get the conclusion of the comparison of the clinical efficacy of the two surgical plans. In addition, possible predictive factors such as age, gender, age of onset, length of disease course, scale baseline score, preoperative brain PET-CT function analysis and other possible predictive factors are added for analysis, in order to find predictive factors that can guide the choice of surgical options.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients confirmed Meige sydrome
排除标准
- •Patients who cannot finish the neurosurgery or the postoperative evaluation
结局指标
主要结局
Symptom
时间窗: 2 years
spasm of eyelid
complications
时间窗: 2 years
Postoperative complications
次要结局
- quality of life(2 years)
- depression scale(2 years)
研究者
Liu Ruen
PekingUPH
Peking University People's Hospital
