Evaluation of In-office Bleaching-induced Sensitivity With 2 or 7 Days Interval Between Sessions
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 47
- 试验地点
- 2
- 主要终点
- Tooth sensitivity
研究概览
简要总结
Clinical randomized single-blind trial, used to measure the level of tooth sensitivity (TS) after in-office dental bleaching sessions, on volunteers using a modified visual analog scale (VAS). The investigators selected for this study, 47 participants with color 2M2 or darker (Using 0M1 - 5M3 Vita bleaching shade guide). The investigators performed two bleaching sessions with an acidic 35% hydrogen peroxide gel with either a 1-week or 2-day interval. The investigators recorded the TS up to 48 h with a VAS scale and the color at baseline and 30 days after bleaching with a value-oriented shade guide and a spectrophotometer. The risk and intensity of TS and the color change were compared between the two groups.
详细描述
Two weeks before the bleaching procedures, selected volunteers from the city of Nova Friburgo, (Rio de Janeiro, Brazil) received a dental screening and a dental prophylaxis with pumice and water in a rubber cup and signed an informed consent form.
This was a randomized, single-blind (evaluators), parallel and equivalence trial with an equal allocation rate between groups.
A total of 61 participants were examined in a dental chair to check if they met the inclusion and exclusion criteria. A total of 47 participants were included in this study. The participants were randomly divided in the 2-day and 7-day groups.
During the in-office sessions, participants had the gingival tissue isolated of the teeth using a light-cured resin dam (Top Dam, FGM, Joinville, SC, Brazil). After that, a 2% Potassium nitrate and Sodium fluoride desensitizer gel (Desensitize 2%, FGM) was applied for 15 minutes before dental bleaching. This gel was removed and the 35% hydrogen peroxide gel (Whiteness HP, FGM, Joinville, Brazil) was applied in three 15-min applications according to the manufacturer's directions in all upper and lower incisors, canines and premolars. After 2 days (2-day group) and 7 days (7-day group), this procedure was repeated using the same protocol.
Color evaluation was performed before and 30 days after the end of the bleaching treatment using a subjective (value oriented shade guide Vita Lumin, Vita Zahnfabrik, Bad Sackingen, Germany) and an objective method (Easyshade spectrophotometer, Vident, Brea, CA, USA). Color evaluation was done in a room under artificial lightning conditions without interference from outside light.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •The selected volunteers should:
- •Present Good general state of health
- •Be at least 18 years of age
- •Have an acceptable oral hygiene
- •Present the upper and lower arches without absence of teeth of first premolar right to the left first premolar.
- •Have anterior teeth with any kind of restoration.
- •Be No smoker
- •Have the upper right canine with color 2M2 or darker
排除标准
- •The selected volunteers should not:
- •Have medical history of diseases that can affect the results of the study
- •Have made use of cigarettes in the last 30 days
- •Have some important pathology in the oral cavity
- •Be pregnant
- •Be breastfeeding
- •Have moderate advanced periodontal disease;
- •Have consumed drugs, alcohol or any medication that can cover the results, as other types of anti-inflammatories or painkillers;
- •Have used products indicated for dental sensitivity, as desensitizing toothpaste or similar product
- •Present gingival recession
- •Present exacerbated hypersensitivity history
研究组 & 干预措施
Bleaching 7 days interval
Participants will undergo 2 sessions of in-office dental bleaching, using a 35% Hydrogen Peroxide bleaching gel, with 7 days of interval between sessions. Bleaching gel will be used in 3 15-minutes applications as indicated by the manufacturer. A 2% Potassium Nitrate and Sodium Fluoride desensitizing gel will be applied 15 minutes before the dental bleaching procedure, in both sessions.
干预措施: In-office Dental Bleaching Conventional (Procedure)
Bleaching 2 days interval
Participants will undergo 2 sessions of in-office dental bleaching, using a 35% Hydrogen Peroxide bleaching gel, with 2 days of interval between sessions. Bleaching gel will be used in 3 15-minutes applications as indicated by the manufacturer. A 2% Potassium Nitrate and Sodium Fluoride desensitizing gel will be applied 15 minutes before the dental bleaching procedure, in both sessions.
干预措施: In-office Dental Bleaching Alternative (Procedure)
结局指标
主要结局
Tooth sensitivity
时间窗: 48 hours after dental bleaching session
Visual Analogic Scale (0-100) for Tooth Sensitivity. In this case, zero means no sensitivity (a better outcome) and 100 means higher sensitivity (worse outcome).
Tooth sensitivity
时间窗: 1 hour after dental bleaching session
Visual Analogic Scale (0-100) for Tooth Sensitivity. In this case, zero means no sensitivity (a better outcome) and 100 means higher sensitivity (worse outcome).
Tooth sensitivity
时间窗: 24 hours after dental bleaching session
Visual Analogic Scale (0-100) for Tooth Sensitivity. In this case, zero means no sensitivity (a better outcome) and 100 means higher sensitivity (worse outcome).
次要结局
- Subjective Color change(30 days after dental bleaching session)
- Objective Color change(30 days after dental bleaching session)