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Clinical Trials/NCT01236989
NCT01236989UnknownNot Applicable

Anatomical Liver Resection by Means of Ultrasound-guided Vessel Compression Versus Non-anatomical Resection for Hepatocellular Carcinoma: A Randomized Controlled Trial

University of Milan1 site in 1 country120 target enrollmentStarted: January 1, 2011Last updated:
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Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Enrollment
120
Locations
1
Primary Endpoint
the prognostic impact of anatomical resection by means of intraoperative ultrasound (IOUS) guided vessel compression versus nonanatomical resection in terms of disease free and overall survival
Study OverviewStudy DesignEligibility CriteriaArms & InterventionsOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

Prognostic impact of AR vs NAR

Detailed Description

Whether anatomical is better than non anatomical resection for HCC is still debated. This prospective randomized study aimed to address which approach is better in terms of patients prognosis.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •patient affected by single HCC
  • •patients in whom liver resection is indicated
  • •HCC without vascular invasion and/or thrombosis

Exclusion Criteria

  • •multinodular HCC
  • •metastatic disease
  • •spontaneous tumor rupture

Arms & Interventions

Anatomical resection

Experimental

Intervention: anatomical liver resection (Procedure)

Non-anatomical resection

Active Comparator

Intervention: Non-anatomical liver resection (Procedure)

Outcomes

Primary Outcomes

the prognostic impact of anatomical resection by means of intraoperative ultrasound (IOUS) guided vessel compression versus nonanatomical resection in terms of disease free and overall survival

Time Frame: 5-years

Secondary Outcomes

  • the impact of anatomical resection versus non-anatomical resection in terms of postoperative mortality and morbility(30 and 90 days)

Investigators

Sponsor Class
Other

Study Sites (1)

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