The study for the hepatoprotective effect of steroid administration before hepatectomy in major hepatectomy with extrahepatic bile duct resection.
Phase 2
- Conditions
- patients who are scheduled to undergo major hepatectomy with extrahepatic bile duct resection.
- Registration Number
- JPRN-UMIN000025039
- Lead Sponsor
- agoya University
- Brief Summary
There were no significant differences between the groups in the incidence of grade B/C postoperative liver failure (control group, n = 8, 17%; steroid group, n = 4, 8%; p = 0.188) and other complications. Serum bilirubin levels on PODs 2 and 3 were significantly lower in the steroid group than those in the control group; however, these median values were within normal limits in both groups.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 94
Inclusion Criteria
Not provided
Exclusion Criteria
1. Patients who reject to participate in the study. 2. Patients who are not eligible to participate in the study (by decision of the investigators).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The incidence rate of posthepatectomy liver failure.
- Secondary Outcome Measures
Name Time Method Postoperative liver injury. Postoperative complications other than the liver failure. Postoperative inhospital day.