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Clinical Trials/NCT00184392
NCT00184392
Completed
Not Applicable

Debridement After Functional Endoscopic Sinus Surgery

Norwegian University of Science and Technology2 sites in 1 country60 target enrollmentJanuary 2005

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Acute Recurrent Rhinosinusitis
Sponsor
Norwegian University of Science and Technology
Enrollment
60
Locations
2
Primary Endpoint
Adhesions in middle meatus or not
Status
Completed
Last Updated
12 years ago

Overview

Brief Summary

The goal of this study is to increase knowledge about how to treat patients after sinus surgery.

Detailed Description

Many surgeons consider the postoperative treatment after sinus surgery as important for the outcome as the surgery itself. However, postoperative treatment regimes differ considerably between surgeons. They include non-intervention, frequent in-office endoscopic debridement, stenting of the middle meatus, saline douching or irrigation of the nose, or combinations of these measures in various ways. The lack of consensus is unfortunate. It indicates a lack of knowledge about how to treat these patients optimally after surgery. This is partly due to a lack of internationally acknowledged randomised, comparative, prospective studies on the effects of the various postoperative measures and their interactions. Accordingly, some patients may receive a too intensive postoperative follow up, with unnecessary frequent visits with the doctor, unnecessary bleeding and inconvenience from unnecessary debridement/cleaning of the nose, and increased costs due to unnecessary medication. Conversely, there may be patients that receive too little attention in the postoperative period, and thus may have a suboptimal result of the operation. Frequent cleaning/debridement of the nose after sinus surgery is believed to improve the outcome of functional endoscopic sinus surgery (FESS). However, the scientific data on its effects are limited. The purpose of this study was to evaluate the effects of cleaning/ debridement of the middle meatus 5-7 days and 12-14 days after sinus surgery in a randomized, partly blinded, controlled clinical trial.

Registry
clinicaltrials.gov
Start Date
January 2005
End Date
September 2007
Last Updated
12 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Inclusion criteria are acute recurrent rhinosinusitis and chronic rhinosinusitis. The investigators used the classification of rhinosinusitis proposed by Lanza and Kennedy.

Exclusion Criteria

  • Previous FESS
  • Systemic disease with affection of the nose (Wegener's granulomatosis, cystic fibrosis, Kartagener's syndrome, sarcoid)
  • Primary ciliary dyskinesia
  • Pregnancy
  • Septoplasty in the same surgery
  • Ongoing treatment for cancer

Outcomes

Primary Outcomes

Adhesions in middle meatus or not

Time Frame: 3 months

synechia between concha media and lateral nasal wall 0=no adhesion 1=adhesions present

Secondary Outcomes

  • Pain due to cleaning of the nose(1 and 2 weeks after surgery)
  • nasal congestion after surgery(2 weeks)
  • Does cleaning of the nose reduce: crusts in the nose 14 days after surgery(2 weeks after surgery)
  • the tendency to post operative infections(3 months)
  • Does debridement increase bleeding from the nose the first 14 days after surgery(2 weeks)

Study Sites (2)

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