Investigation of Ultrasonographic Predictors of Difficult Intubation and Difficult Mask Ventilation in Adult Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- Number of Participants with Difficult Intubation
研究概览
简要总结
Difficult airway management is a major cause of perioperative complications. Standard bedside airway assessment tests may have limited ability to predict difficult intubation and difficult mask ventilation. This prospective observational study aims to evaluate whether preoperative ultrasound measurements of airway structures (such as skin-to-epiglottis distance, tongue thickness, and pre-epiglottic space) can predict difficult intubation and difficult mask ventilation in adult patients undergoing surgery under general anesthesia.
详细描述
This prospective observational cohort study was conducted to evaluate the predictive value of preoperative ultrasonographic airway measurements for difficult intubation and difficult mask ventilation in adult patients undergoing elective surgery under general anesthesia. A total of 400 patients aged 18-70 years with ASA physical status I-III were included. Before induction of anesthesia, standard clinical airway assessment tests were recorded, and ultrasound measurements were performed to assess airway-related anatomical structures. Ultrasonographic parameters included skin-to-epiglottis distance, skin-to-thyroid cartilage distance, thyroid cartilage-to-epiglottis distance, pre-epiglottic space depth, tongue thickness, and hyomental distance measurements.
Intraoperatively, mask ventilation and intubation conditions were documented. Difficult intubation was defined as requiring two or more intubation attempts. Difficult mask ventilation was defined as the need for two-handed mask ventilation or inability to ventilate adequately using a face mask. The primary objective was to determine the association between ultrasonographic measurements and difficult intubation
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 18-70 years
- •ASA physical status I-III
- •Elective surgery under general anesthesia requiring orotracheal intubation
- •Written informed consent
排除标准
- •Refusal to participate
- •Emergency surgery
- •Known upper airway pathology or previous airway surgery
- •Restricted mouth opening (<3 cm)
- •Cervical spine instability or significant limitation of neck mobility
- •Morbid obesity (BMI ≥40 kg/m²)
- •Obstructive upper airway masses (e.g., head and neck tumors)
- •Prior neck radiotherapy
- •Clinically relevant neck masses
- •Major facial/mandibular trauma or craniofacial anomalies
研究组 & 干预措施
Cohort 1: Adult patients undergoing surgery under general anesthesia
Adult patients (18-70 years, ASA I-III) scheduled for elective surgery under general anesthesia requiring orotracheal intubation. Preoperative clinical airway assessment and ultrasonographic airway measurements were recorded, and intraoperative intubation and mask ventilation outcomes were evaluated
结局指标
主要结局
Number of Participants with Difficult Intubation
时间窗: During induction of anesthesia (intraoperative)
Difficult intubation was defined as requiring two or more intubation attempts (≥2 attempts) during induction of general anesthesia.
Number of Participants with Difficult Mask Ventilation
时间窗: During induction of anesthesia (intraoperative)
Difficult mask ventilation was defined as the need for two-handed mask ventilation or inability to ventilate adequately using a face mask
次要结局
未报告次要终点
研究者
Serkan TELLİ
Principal Investigator
Kutahya Health Sciences University