Vision therapy for amblyopia in older children and adults

Completed

• Conditions: Amblyopia ex anopsia,

• Registration Number: CTRI/2021/04/033167
• Lead Sponsor: Post Graduate Institute of Medical Education and Research Research Grant Cell

Brief Summary

Amblyopia is a decreased visual acuity without any identifiableorganic cause in the eye. It is the main cause of poor unilateral vision inchildren and believed to occur during a period of neural plasticity early inlife. Traditional amblyopia treatment is based on depriving the ‘‘good†eyewhile optimizing the visual experience of the amblyopic eye mainly byocclusion. The benefit of patching fades as the child grows and there iscurrently no treatment available to successfully treat amblyopia in a child morethan 9 years. In children more than 10 years only one-quarter–one-half of children responding tocombined treatment of spectacles and patching.

Recentstudies suggest that repetitive practice can improve performance on a varietyof visual tasks in adult humans with normal visual capacities. Studies onperceptual learning indicate that practice can result in improvement of manyvisual tasks in adults, including visual detection or discrimination oforientation, Vernier offset, stereo information, and contrast sensitivityfunction. Our hypothesis is that perceptual learning will modify visualfunctions in even adult patients of amblyopia and improve visual acuity,contrast and stereopsis in these patients. The aim of our study is to assessthe efficacy of perceptual learning exercises in older children and adults withamblyopia who have failed patching.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-05-05
• Study Completion: 2023-03-31
• Last Update Posted: 2024-05-09

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

ALL TYPES OF Amblyopic patients presenting between 9 to 30 years will be recruited.

Exclusion Criteria

• Patients with diplopia/epilepsy/chronic migraines/pregnancy/attention disorder.
• Patients who have received any pharmacotherapy in past/present for amblyopia.
• Patients who fail to complete the required follow up or do not complete therapy will be excluded from the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Best corrected visual acuity	6 months and one year

Secondary Outcome Measures

Name	Time	Method
Stereopsis and Contrast Sensitivity testing	6 months and one year

Trial Locations

Locations (1)

Post Graduate Institute of Medical Education and Research; 🇮🇳 Chandigarh, CHANDIGARH, India

Post Graduate Institute of Medical Education and Research

🇮🇳Chandigarh, CHANDIGARH, India

SAVLEEN KAUR

Principal investigator

017227561111

mailsavleen@gmail.com