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临床试验/CTRI/2021/04/033167
CTRI/2021/04/033167已完成不适用

Vision therapy for amblyopia in older children and adults

Post Graduate Institute of Medical Education and Research Research Grant Cell1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2021年5月5日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
60
试验地点
1
主要终点
Best corrected visual acuity

研究概览

简要总结

Amblyopia is a decreased visual acuity without any identifiableorganic cause in the eye. It is the main cause of poor unilateral vision inchildren and believed to occur during a period of neural plasticity early inlife. Traditional amblyopia treatment is based on depriving the ‘‘good†eyewhile optimizing the visual experience of the amblyopic eye mainly byocclusion. The benefit of patching fades as the child grows and there iscurrently no treatment available to successfully treat amblyopia in a child morethan 9 years. In children more than 10 years only one-quarter–one-half of children responding tocombined treatment of spectacles and patching.

Recentstudies suggest that repetitive practice can improve performance on a varietyof visual tasks in adult humans with normal visual capacities. Studies onperceptual learning indicate that practice can result in improvement of manyvisual tasks in adults, including visual detection or discrimination oforientation, Vernier offset, stereo information, and contrast sensitivityfunction. Our hypothesis is that perceptual learning will modify visualfunctions in even adult patients of amblyopia and improve visual acuity,contrast and stereopsis in these patients. The aim of our study is to assessthe efficacy of perceptual learning exercises in older children and adults withamblyopia who have failed patching.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Outcome Assessor Blinded

入排标准

年龄范围
9.00 Year(s) 至 30.00 Year(s)(—)
性别
All

入选标准

  • •ALL TYPES OF Amblyopic patients presenting between 9 to 30 years will be recruited.

排除标准

  • •Patients with diplopia/epilepsy/chronic migraines/pregnancy/attention disorder.
  • •Patients who have received any pharmacotherapy in past/present for amblyopia.
  • •Patients who fail to complete the required follow up or do not complete therapy will be excluded from the study.

结局指标

主要结局

Best corrected visual acuity

时间窗: 6 months and one year

次要结局

  • Stereopsis and Contrast Sensitivity testing(6 months and one year)

研究者

发起方
Post Graduate Institute of Medical Education and Research Research Grant Cell
申办方类型
Research institution and hospital

研究点 (1)

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