Is stroke neurodegenerative? A longitudinal study of changes in brain volume and cognition following stroke (CANVAS: Cognition And Neocortical Volume After Stroke)

Austin Health0 个研究点目标入组 175 人开始时间: 2016年7月25日最近更新: 2020年3月3日

适应症

试验速览

暂无简介。

•Inclusion criteria for the stroke group include:
•1. Clinical ischaemic stroke;
•2. Aged greater than 18 years;
•3. Able to have cognitive testing and MRI scan; and
•4. Able to give informed consent.
•Inclusion criteria for healthy controls are the same, excluding, of course, the stroke diagnosis.

•Exclusion criteria for stroke patients and control participants are the same. These include:
•1. Significant medical comorbidities precluding participation in cognitive testing, or making survival for 3 years unlikely;
•2. Normal exclusion criteria for MRI; e.g., implanted metal, severe claustrophobia;
•3. Pre-existing dementia;
•4. Pregnancy, as a precaution to prevent exposing them to multiple MRI scans in a 12-month period;
•5. People in existing dependent or unequal relationships with any member of research team, to protect against coercion.

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