Non-invasive Measurement of Central Hemodynamics by Electrical Impedance Tomography

Not Applicable

Withdrawn

• Conditions: Comparison of Availability for Prediction of Volume Responsiveness; Comparison of Limits of Agreement for Invasive and Non-invasive Measurement of Stroke Volume Variation
• Interventions: Other: volume loading

• Registration Number: NCT01412970
• Lead Sponsor: Universitätsklinikum Hamburg-Eppendorf

Brief Summary

The purpose of this study is to evaluate the ability to measure central hemodynamics and heart-lung interactions non-invasively by electrical impedance tomography and compare it to clinically established hemodynamic monitoring.

Detailed Description

The purpose of this study is to evaluate the ability to measure central hemodynamics and heart-lung interactions non-invasively by electrical impedance tomography and compare it to clinically established hemodynamic monitoring.

Study Timeline

• Study First Submitted: 2011-08-08
• Study First Submitted QC: 2011-08-08
• Study First Posted: 2011-08-09
• Study Start: 2016-07
• Primary Completion: 2016-12
• Study Completion: 2017-03
• Status Verified: 2022-08
• Last Update Submitted: 2022-08-26
• Last Update Posted: 2022-08-30

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Age >18 years
• Indication for advanced invasive hemodynamic monitoring due to operative procedure
• Necessity of postoperative invasive ventilation

Exclusion Criteria

• Age <18 years
• known affections cardiac function
• presence of cardiac arrhythmias
• contraindication for placement of central venous or femoral artery catheter

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
study group	volume loading	comparison of ability to predict volume responsiveness and precision of measurement of stroke volume variation assessed by electrical impedance tomography in comparison to clinically established invasive hemodynamic monitoring devices, i.e. arterial pulse contour analysis during volume loading procedures

Primary Outcome Measures

Name	Time	Method
Ability to assess volume responsiveness by electrical impedance tomography	within 3 hrs after surgical procedure	Assessment of volume responsiveness by electrical impedance tomography in mechanically ventilated patients by measurement of stroke volume variations under stepwise volume loading

Secondary Outcome Measures

Name	Time	Method
precision of estimation of non invasive measurement of stroke volume variation	within 3 hours after surgery	precision of estimation of non invasive measurement of stroke volume variation by electrical impedance tomography in comparison to clinically established, invasive advanced hemodynamic monitoring devices

Trial Locations

Locations (1)

University Medical Center Hamburg-Eppendorf; 🇩🇪 Hamburg, Germany