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Clinical Trials/NCT05228938
NCT05228938
Terminated
Not Applicable

Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) Salpingo-oophorectomy or Bilateral Salpingectomy Compared With Laparoscopic Approach. Prospective Study-A New Approach.

HaEmek Medical Center, Israel1 site in 1 country1 target enrollmentMay 29, 2022
ConditionsSalpingectomy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Salpingectomy
Sponsor
HaEmek Medical Center, Israel
Enrollment
1
Locations
1
Primary Endpoint
Successful removal of the fallopian tubes or adnexa without a need to convert to another technique.
Status
Terminated
Last Updated
2 years ago

Overview

Brief Summary

Objective: To compare the vNOTES approach versus conventional laparoscopic approach used in elective Salpingo-oophorectomy surgery for benign disease or bilateral salpingectomy for sterilization.

Study design: Prospective cohort, randomized controlled trial.

Study population: Planned Salpingo-oophorectomy for benign disease or bilateral salpingectomy for sterilization.

Primary outcome - Adherence to planned surgical route, intra-operative parameters & complications, post-operative parameters & complications, rate of satisfaction.

Detailed Description

Objective: To compare the vNOTES approach versus conventional laparoscopic approach used in elective Salpingo-oophorectomy surgery for benign disease or bilateral salpingectomy for sterilization. Study design: Prospective cohort, randomized controlled trial. Study population: women aged over 18 who are planned to elective Salpingo-oophorectomy for benign disease or bilateral salpingectomy for sterilization. Primary outcome - Removal of the ovaries and/or fallopian tubes according to the allocated technique, without conversion. Secondary outcome - Duration of the surgical procedure, Duration of hospital admission (after surgery), The need for analgesics, and pain Numerical Rating Scale score , Post operation infection (up to 4 weeks from surgery), Need for medical examination/treatment or appearance of surgical complication up to 4 weeks form surgery (using Clavin Dindo Class), Bleeding assessment during surgery, Dyspareunia assessment - up to 3 months from surgery, Patient satisfaction from the surgical procedure will be measured with Patient Global Impression of Improvement (PGI-I).

Registry
clinicaltrials.gov
Start Date
May 29, 2022
End Date
December 31, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Meirav Braverman

Principal Investigator

HaEmek Medical Center, Israel

Eligibility Criteria

Inclusion Criteria

  • Women aged between 18 and 80 years.
  • women who seek for definitive surgical sterilisation.
  • women who planed for Elective bilateral salpingectomy or Salpingo-oophorectomy for a non-malignant indication

Exclusion Criteria

  • history of rectal surgery.
  • rectovaginal endometriosis
  • suspected malignancy
  • History of pelvic inflammatory disease.
  • active lower genital tract infection.
  • Virgo women
  • Failure to provide written informed consent prior to surgery

Outcomes

Primary Outcomes

Successful removal of the fallopian tubes or adnexa without a need to convert to another technique.

Time Frame: Intraoperative

Number of Participants With Removal of the ovaries and/or fallopian tubes according to the allocated technique.

Secondary Outcomes

  • Intra- Operative Complications(Intraoperative)
  • Postoperative Complications(During the first six weeks after the surgical intervention)
  • Duration of surgical intervention(Intraoperative)
  • The use of analgetic drugs for postoperative pain(During the first week after the surgical intervention)
  • Hospital Readmission(During the first six weeks after the surgical intervention)
  • Patient satisfaction from the surgical procedure(At 3 months after the surgical intervention)
  • Duration of hospital admission after surgical intervention(from time of admission up to time of discharge from hospital)
  • Bleeding assessment during surgical intervention(Intraoperative)
  • Post operation infection(detected during the first six weeks of surgery)
  • Vaginal Pain During Sexual Intercourse at Three Months(At 3 months after the surgical intervention)
  • Postoperative pain scores(During the first seven days after the surgical intervention)

Study Sites (1)

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