Skip to main content
Clinical Trials/NCT04485299
NCT04485299
Unknown
Phase 2

Quantitative Clinical Assessment of Bifluorid 10 Versus Varnish Fluoride on The Exposed Hypersensitive Cervical Dentin in Adult Patient: A Randomized Clinical Trial

Cairo University0 sites68 target enrollmentOctober 2020

Overview

Phase
Phase 2
Intervention
Bifluorid 10 ,VOCO
Conditions
Hypersensitivity
Sponsor
Cairo University
Enrollment
68
Primary Endpoint
Dentin hypersensitivity
Last Updated
5 years ago

Overview

Brief Summary

Aim of the study will be conducted to compare the efficacy of bifluoride (NaF and CaF) versus conventional fluoride varnish (Sodium Flouride) in the management of hypersensitivity of exposed cervical area in adult patients over 2 month

Registry
clinicaltrials.gov
Start Date
October 2020
End Date
January 2021
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Zaid Yousef Fakhry Al khateeb

Master's degree student - faculty of dentistry

Cairo University

Eligibility Criteria

Inclusion Criteria

  • Healthy patient with free medical history.
  • Age range 18-60 years old.
  • Good oral hygiene
  • Patients suffering from pain due to dentin hypersensitivity.
  • Patient with sound first molar .

Exclusion Criteria

  • Patients using desensitizing agents, receiving periodontal treatment or had received nonsurgical periodontal treatment in the last three months.
  • Patient wearing orthodontic appliance.
  • Patient with teeth having a painful condition involving the pulp and periapical region.
  • Patients who had allergy to materials will be used in the study.
  • Pregnancy.
  • Patient who does not consent to participation.
  • Patient who does not attend to the follow up.
  • A patient who has a carious first molar.

Arms & Interventions

bifluorid 10 varnish

Bifluorid 10 (NaF and CaF) lead to reduce the dentin hypersensitivity, the sodium fluoride (NaF) dissociates and releases F ions, that diffuse through the tubules and then precipitates as calcium fluoride as a consequence of the high of calcium content in saliva and dentinal fluid ,The calcium fluoride (CaF) present in the varnish composition diffuses into the tubules and block the canal with a semi-permanent protective layer.The calcium fluoride is added to block the dentin tubules mechanically, by the combination with the calcium fluoride resulted from the sodium fluoride reaction to the calcium of dentin.

Intervention: Bifluorid 10 ,VOCO

sodium fluoride varnish

Topical application of varnish fluoride (sodium fluoride NaF) effect on exposed dentine as a desensitizing agent, the varnish fluoride process is caused by the reaction between NaF and calcium ions resulting in calcium fluoride crystals being deposited on the openings of the dentinal tubules that decrease pain.

Intervention: Sodium Fluoride 5% Dental Varnish

Outcomes

Primary Outcomes

Dentin hypersensitivity

Time Frame: 8 weeks

measurement of dentin hypersensitivity by VAS scale

Secondary Outcomes

  • Dentinal tubule occlusion(8 weeks)

Similar Trials