Endoscopic functional luminal imaging probe to assess esophagogastric junction distensibility for nonerosive reflux disease

Bundang CHA General Hospital0 sites900 target enrollmentTBD

Overview

No summary available.

Registry

who.int

Start Date

TBD

End Date

September 30, 2018

Last Updated

6 years ago

Study Type

Observational Study

Sex

All

Sponsor

Bundang CHA General Hospital

•All patients who were between 15 and 79 years old, with reflux symptoms, and scheduled to undergo a screening gastroscopy and EndoFLIP® were included in this study. According to the results, patients with erosive esophagitis, determined by gastroscopy, were referred to the ERD group, while patients with no erosive esophagitis, but with abnormalities observed over 24\-hour pH monitoring were classified as the NERD group.12 Healthy controls were on no regular medications and had no symptoms of reflux disease, but did have nonspecific symptoms, such as dyspepsia or abdominal discomfort.

•(1\) unable to receive a gastroscopy or EndoFLIP®; (2\) unable to provide informed consent; (3\) hemodynamic instability (systolic blood pressure \[SBP] \< 90 mmHg), or if the peripheral oxygen saturation (SpO2\) was 90% in room air, or \< 95% on 2 L/min of oxygen at baseline before the procedure; (4\) psychological problems; (5\) acute severe infection; (6\) evidence of esophageal
•motility disorder on esophageal manometry.