Expression of IRAK1 Gene rs1059703-related Single- Nucleotide Polymorphisms in Egyptian Patient With Rheumatoid Arthritis

Not Applicable

Recruiting

• Conditions: Rheumatoid Arthritis (RA)
• Interventions: Genetic: PCR polymorphism

• Registration Number: NCT05588817
• Lead Sponsor: Sohag University

Brief Summary

Rheumatoid arthritis (RA) is known as a long-lasting inflammatory autoimmune disease affecting the diarthrodial joints, which is diagnosed by inflammation and hyperplasia in synovium, generation of RF and anti-citrullinated protein antibody (ACPA), deformity of cartilage and bone, systemic injuries involving cardiovascular, pulmonary, psychological, and skeletal disorders (McInnes and Schett., 2011).

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Status Verified: 2022-10
• Study First Submitted: 2022-10-18
• Study First Submitted QC: 2022-10-19
• Last Update Submitted: 2022-10-19
• Study First Posted: 2022-10-20
• Last Update Posted: 2022-10-20
• Study Start: 2022-12-30
• Primary Completion: 2023-12-01
• Study Completion: 2023-12-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 90

Inclusion Criteria

• approval to sign an informed written consent, patient diagnosed rheumatoid arthritis, patient age range 17-85 year and both sexes are included.

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Exclusion Criteria

• Refusal to sign an informed written consent and patient with other autoimmune disease.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group 1	PCR polymorphism	Normal control
Group 2	PCR polymorphism	Diagnosed Rhomatoid arthritis patients

Primary Outcome Measures

Name	Time	Method
rs1059703 PCR polymorphism in rhomatoid arthritis patients	1 year	PCR polymorphism

Trial Locations

Locations (1)

Sohag university hospital; 🇪🇬 Sohag, Egypt