Effect Of Whole Body Vibration Versus Weight Bearing Exercises On Osteoporosis In Breast Cancer Patients After Chemotherapy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- Assessing the change in bone mineral density
研究概览
简要总结
Chemotherapy can damage bone marrow and therefore impair the production of white blood cells, platelets and red blood cells with the resulting anemia and osteoporosis.
详细描述
Purposes of this study were:
- To determine the therapeutic efficacy of the whole-body vibration (WBV) in improving osteoporosis in breast cancer patients after receiving chemotherapy within 3-6 months.
- To determine the therapeutic efficacy of the weight bearing exercise in improving osteoporosis in breast cancer patients after receiving chemotherapy within 3-6 months.
- To gain knowledge about the whole-body vibration (WBV) and the weight bearing exercise in improving osteoporosis in breast cancer patients after receiving chemotherapy within 3-6 months.
- To share in designing an ideal protocol for the treatment of the osteoporosis in breast cancer patients after receiving chemotherapy within 3-6 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 35 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Breast cancer patients after receiving chemotherapy within 3-6 months and complaining from osteoporosis.
- •Their age ranges from 35-55 years old.
- •All patients will have the same medical and nursing care.
- •All the patients will receive a good explanation of treatment and measurement device.
- •They are neurologically free.
排除标准
- •Patients will be excluded from this study for any of the following causes:
- •Uncooperative patients.
- •Instability of patient's medical condition.
- •Association of another medical problem.
- •Patients who have diabetes.
- •Patients who have history of medical chronic relevant diseases.
- •Patients who have acute or chronic hepatitis.
- •Patients who have pacemaker.
- •Patients who have genitourinary infections.
研究组 & 干预措施
Whole body vibration group
In this group (the first study group) fifteen breast cancer patients after receiving chemotherapy within 3-6 months and complaining from osteoporosis were received the whole body vibration, 20 minutes 3 times per week for 2 months and drug therapy (vitamin D supplements and calcium).
干预措施: Whole body vibration group (Other)
Whole body vibration group
In this group (the first study group) fifteen breast cancer patients after receiving chemotherapy within 3-6 months and complaining from osteoporosis were received the whole body vibration, 20 minutes 3 times per week for 2 months and drug therapy (vitamin D supplements and calcium).
干预措施: vitamin D supplements and calcium (Drug)
Weight bearing exercises group
In this group (the second study group) fifteen breast cancer patients after receiving chemotherapy within 3-6 months and complaining from osteoporosis were received aerobic exercise on treadmill as form of weight bearing exercise 20 minutes 3 times per week for 2 months and drug therapy (vitamin D supplements and calcium).
干预措施: Weight bearing exercises (Other)
Weight bearing exercises group
In this group (the second study group) fifteen breast cancer patients after receiving chemotherapy within 3-6 months and complaining from osteoporosis were received aerobic exercise on treadmill as form of weight bearing exercise 20 minutes 3 times per week for 2 months and drug therapy (vitamin D supplements and calcium).
干预措施: vitamin D supplements and calcium (Drug)
drug therapy group
In this group (control group) fifteen breast cancer patients after receiving chemotherapy within 3-6 months and complaining from osteoporosis were received only drug therapy (vitamin D supplements and calcium. Measurements were conducted before starting the treatment as a first record, at end of the second month of treatment as second record and make follow up after 3 months as final record.
干预措施: vitamin D supplements and calcium (Drug)
结局指标
主要结局
Assessing the change in bone mineral density
时间窗: at baseline and after 2 months of intervention
By using DEXA (dual-energy X-ray absorptiometry): Dual-energy X-ray absorptiometry (DEXA) is a clinically proven method of measuring bone mineral density (BMD) in the lumbar spine, proximal femur, forearm, and whole body. It is used primarily in the diagnosis and management of osteoporosis and other disease states characterized by abnormal BMD, as well as to monitor response to therapy for these conditions .
次要结局
未报告次要终点
研究者
Eman Mahrous Abdel-Hamed Ahmed Elgendy
Principal Investigator
Cairo University