Measurement of mouthwash anti-viral activity against COVID-19 (MOMA)

Cardiff University0 个研究点目标入组 78 人开始时间: 2020年11月9日最近更新: 2022年3月7日

适应症

试验速览

2022 Preprint results in https://doi.org/10.1101/2022.02.16.22270842 (added 18/02/2022)

•Eligible patients will be approached and recruited from COVID in-patient wards within Cardiff and Vale University Health Board, Betsi Cadwaladr University Health Board, University Hospitals Bristol NHS Foundation Trust and Cwm Taf Morganwg University Health Board. Only patients who are deemed well enough and able to provide informed consent by their local clinical teams will be approached to take part in the study. Specific inclusion criteria are:
•1. Adults aged =18 years
•2. With positive SARS-CoV-2 carriage by RT-PCR within 14 days
•3. Capable of using the mouthwash required by the trial
•4. Capacity and capability to give informed consent to take part in the trial

•1. Known or suspected intolerance or hypersensitivity to povidone-iodine or other study materials (or closely related compounds) or any of their stated ingredients
•2. Known pregnancy, currently breastfeeding or women of childbearing age without effective contraception
•3. Current requirement for invasive or non-invasive ventilation; or planned within next 6 hours
•4. Known dermatitis herpetiformis (Duhring's disease)
•5. Inability to communicate in English or read English

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