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Feasibility study of Carbon-Ion Radiotherapy for Re-Irradiation of Locoregionally Recurrent or Metastatic Lung Tumors

Not Applicable
Conditions
ung cancer or metastatic lung tumor
Registration Number
JPRN-UMIN000029313
Lead Sponsor
Hospital of the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Sciences and Technology
Brief Summary

Data of 95 patients with prior intrathoracic carbon-ion radiotherapy who were treated with reirradiation with carbon-ion radiotherapy at our institution between 2006 and 2016 were retrospectively analyzed. Regarding severe toxicities, 1 patient experienced each of the following. Grade 5 bronchopleural fistula, Grade 4 radiation pneumonitis, Grade 3 chest pain, and Grade 3 radiation pneumonitis. The 2-year local control and overall survival rates were 54.0% and 61.9%, respectively. In conclusion, reirradiation with carbon-ion radiotherapy was associated with relatively low toxicity and moderate efficacy.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
95
Inclusion Criteria

Not provided

Exclusion Criteria

The presence of other primary cancers

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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