Efficacy Of Sahacharadi Taila Uttar Basti In The Management Of Chronic Lower UTI In Females .

Phase 2/3

Not yet recruiting

Conditions: Urinary tract infection, site notspecified. Ayurveda Condition: MUTRAKRUCCRAM,

Registration Number: CTRI/2025/04/084558

Lead Sponsor: Institute of Teaching and Research in Ayurveda Jamnagar

Brief Summary: Urinary tract infection may be conveniently divided into lower and upper tract infection. Lower urinary tract infections (LUTI) also known as uncomplicated urinary tract infection is a bacterial infection of the bladder and associated structures. LUTI is the most common bacterial infection managed in general practice. *Mutrakrichhram*, the disease of *Mutravaha Srotas* is a condition where person experiences difficulty in micturition. *Uttar Basti* is one among *Panchakarma* treatments. It is the *Basti* administered through the urinary passage in men and women and also through vagina. Since this imparts extraordinary benefits it is called as *Uttar Basti* . The global prevalence of UTI is around 150 million per year. Research has highlighted a prevalence range for UTIs in Indian women from 3.14% to 19.87%. It is highest in young women (18 - 37 years old) and older men (> 68 years old) .As the prevalence of this disease is very high especially in females and it has become a major health problem affecting large scale of population this disease has been selected. Though there are research works related to the oral administration in *Mutrakrichhram* but not much on *Uttar Bast*i, this has been considered as an intervention for the same. The standard care for UTI are antibiotics, which are often used in the beginning itself in a wide spread way. Injudicious use of antibiotics makes the people prone to many drug resistance. Considering these factors, an immediate need exists for a strong and safe intervention. *Uttar Basti* has been considered as one of the treatment modality . As *Sahacharadi Taila* has been indicated for *Mutrakrichhram* in classics an approach is made to know the efficacy of the same. In this trial it is to evaluate and compare the effect of *Sahacharadi Taila Uttar Basti* with Povidone Iodine bladder irrigation in the management of *Mutrakrichhram* (Chronic lower urinary tract infections) in females. 30 patients having 2 or more than 2 signs and symptoms of *Mutrakrichhram* between the age group 18 to 60 years will be selected from OPD and IPD hospital of ITRA, Jamnagar and from special camps in the clinical study. Special diagnostic camps will also be arranged to enrol the patients . The patients will be enrolled into two groups .Group A will be given Uttarbasti with 20 ml Sahacharadi Taila for 7 days and group B will be given bladder irrigation with povidone iodine 10 % ( diluted with normal saline 1;5 ) with *Chandraprabha vat*i 2TDS A/F And *Trnapanchamulakwatha* 10g BD B/F common in both groups . In this study, obtained data will be analyzed on the basis of proper logics and reasoning to find out the Efficacy of *Sahacharadi Taila Uttar Basti* in the management of *Mutrakrichhram* (Chronic lower urinary tract infections) in females and further conclusions will be derived from the study. The data generated during the present study will be presented in a systemic manner and shall be analysed statistically .

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: Female

Target Recruitment: 30

Inclusion Criteria

The only female patients of age 18 to 60 years.
The patients having either dysuria or any other signs and symptoms of Mutrakrichhram (Chronic lower urinary tract infections) 3.
Patients with positive findings for urine R/M examination.
Recurrent / chronic UTI patients ( defined as occurrence of 2 or more UTIs within months or 3 within a year ).

Exclusion Criteria

Patients of age below 18 years and above 60 years.
Patients of acute UTI , acute cystitis, malignancy, congenital deformities of urogenital tract or any abdominal-pelvic pathology.
Systemic diseases like chronic renal failure (CRF), Uncontrolled Hypertension (BP greater than 150/90 mmHg), diabetes mellitus (RBS greater than 140 mg/dl), 4.
Patient of k/c/o Tuberculosis, Paralysis, and Parkinsonism will be excluded.
Known case of cardiac diseases (H/O- MI, IHD).
Patient having HIV, HBsAg, HCV, VDRL positive 7.
Renal failure 8.
Pyelonephritis 9.
Urinary calculi anywhere in the urinary tract 10.
Pregnancy and lactating women and women with sweta pradara .

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Relief in the features of Mutrakrichhram (chronic lower urinary tract infections) as mentioned in diagnostic criteria.	1 DAY, 8 DAYS

Secondary Outcome Measures

Name	Time	Method
Absence of recurrence in follow up period	15 day , 22 day

Trial Locations

Locations (1): Institute of Teaching and Research in Ayurveda, Jamnagar
🇮🇳
Jamnagar, GUJARAT, India
Institute of Teaching and Research in Ayurveda, Jamnagar
🇮🇳Jamnagar, GUJARAT, India
Dr Adithya Divakaran
Principal investigator
9495151067
adhiram1827@gmail.com