The effect of low doses of mirtazapine and quetiapine on sleep and daytime functioning

Not Applicable

Completed

• Conditions: Insomnia; Mental and Behavioural Disorders

• Registration Number: ISRCTN20011041
• Lead Sponsor: GGZ Drenthe

Brief Summary

1. 2017 results in https://www.ncbi.nlm.nih.gov/pubmed/28093029 (added 29/01/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2015-09-02
• Study Start: 2016-03-31
• Last Update Posted: 11 February 2019

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 19

Inclusion Criteria

1. Male
2. Aged between 18-35 years
3. BMI between 18.0-30 kg/m2
4. Absence of clinically relevant health problems
5. History of going to bed from 22.00h to 00.00h on at least 5-7 nights per week, with a reported sleep duration of 6.5-8.5h over the previous 3 months before the start of and during the study

Exclusion Criteria

1. History of sleep disorder or psychiatric illness
2. Family history of sleep disorder or psychiatric disorder
3. Liver disease
4. Cardiovascular disease
5. Alcohol or drug dependence
6. Use of (psychotropic) medication
7. Known intolerance for either mirtazapine or quetiapine

Study & Design

• Study Type: Interventional
• Study Design: Not specified