跳至主要内容
临床试验/CTRI/2020/02/023507
CTRI/2020/02/023507尚未招募不适用

Prevalence of Oral submucous fibrosis in and around population of Vadodara and its relation to type , duration and frequency of habit: A Hospital based observational study.

MP Dental College1 个研究点 分布在 1 个国家目标入组 4,000 人开始时间: 2020年2月22日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
4,000
试验地点
1
主要终点
Very few prevalence studies for Oral submucous fibrosis are carried out in Gujarat population. Also its relation to various types of habit and their actual frequency and duration is not established.

研究概览

简要总结

Oral submucous fibrosis (OSF) is now accepted globally as an Indian disease, having highest malignant potential than any other oral premalignant lesions. Epidemiological evidence strongly indicate the association of the betel quid (BQ) habit and OSF. Other etiological factors suggested are chillies, lime, tobacco, nutritional deficiencies such as iron and zinc, immunological disorders, and collagen disorders. The male-to-female ratio of OSMF varies by region. Recent data suggests that prevalence of OSMF in India has increased from 0.03% to 6.42%.

The hallmark of the disease is submucosal fibrosis that affects most parts of the oral cavity, pharynx and upper third of the esophagus leading to dysphagia and progressive trismus due to rigid lips and cheeks.

Epidemiological survey conducted in Bhavnagar district, Gujarat state diagnosed as suffering from OSMF with a prevalence of 3.2%.

According to the National Report of Global Adult Tobacco Sur­vey conducted in India , the current prevalence of smokeless tobacco use is 25.9 %. There are 30 different types of smokeless products available in India  including zarda, which contains dried and boiled tobacco leaves, limes, areca nut, additives, spices, and tannins.

The hallmark of the disease is submucosal fibrosis that affects most of the parts of oral cavity, pharynx and upper third of the esophagus.

Very few prevalence studies for Oral submucous fibrosis are carried out in Gujarat population. Also its relation to various types of habit and their actual frequency and duration is not established.

This study would be amongst one of the epidemiological studies with large data over the period of 5 years.

研究设计

研究类型
Observational

入排标准

年龄范围
16.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • All Patients diagnosed with different grades of oral submucous fibrosis Clinically and having habit of chewing different forms of areca nut would be included.

排除标准

  • Patients with no areca nut related habits and without evidence of OSMF would be excluded from study.

结局指标

主要结局

Very few prevalence studies for Oral submucous fibrosis are carried out in Gujarat population. Also its relation to various types of habit and their actual frequency and duration is not established.

时间窗: 5years

This study would be amongst one of the epidemiological studies with large data over the period of 5 years.

时间窗: 5years

次要结局

  • Relationship between dose of Tobacco related habits consumped and its relation towards occurence of lesions can be evaluated(5 Years)

研究者

发起方
MP Dental College
申办方类型
Research institution and hospital

研究点 (1)

Loading locations...

相似试验