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临床试验/NCT07356219
NCT07356219进行中(未招募)不适用

The Merits of the Prognostic Nutritional Index for Prediction of the Outcome of Coronary Artery Bypass Grafting Surgery: A Retrospective Observational Study

Benha University0 个研究点目标入组 117 人开始时间: 2025年11月15日最近更新:

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
117

研究概览

简要总结

Coronary artery bypass grafting (CABG) is a major cardiac surgery associated with risks of serious perioperative complications and mortality. Malnutrition and inflammation are known independent risk factors for poor outcomes in patients with coronary artery disease. This retrospective observational study evaluates the Prognostic Nutritional Index (PNI)-a simple score derived from serum albumin and lymphocyte counts-as an objective measure of nutritional and inflammatory status. The research aims to determine how well preoperative PNI and its postoperative changes can predict complications such as acute kidney injury, myocardial infarction, and sternal wound infections in patients undergoing CABG.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
25 Years 至 55 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who underwent CABG surgery.
  • Availability of a signed informed consent form before surgery.

排除标准

  • Other concurrent cardiac surgeries.
  • Presence of malignancy or systemic inflammatory disorders.
  • Active infection or autoimmune disorders.
  • Maintenance on immunosuppressants.
  • Liver disease.
  • Files with missing data.

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohammed El Gazzar

Assistant professor of Cardiothoracic Surgery, Faculty of Medicine, Benha University, Egypt

Benha University

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