NCT06288854UnknownNot Applicable
Efficacy of Olanzapine on Weight Gain in Women with Advanced Stage Gynecologic Cancer Receiving Paclitaxel and Carboplatin Combination Chemotherapy : a Double Blind, Placebo-controlled Randomized Trial
Department of Medical Services Ministry of Public Health of Thailand1 site in 1 country48 target enrollmentStarted: April 3, 2024Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 48
- Locations
- 1
- Primary Endpoint
- Efficacy of olanzapine on weight gain in advanzed stage gynecologic cancer recieving paclitexal and carboplatin chemotherapy
Study Overview
Brief Summary
- Efficacy of olanzapine on weight gain in advanced stage gynecologic cancer
- Proprotion of pateints in advanced stage gynecologic cancer who recieving paclitaxel and carboplatin chemotherapy gain weight on olanzapine or placebo
Detailed Description
-Proprotion of pateints in advanced stage gynecologic cancer who recieving paclitaxel and carboplatin chemotherapy gain weight on olanzapine or placebo
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to 70 Years (Adult, Older Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Advanced stage gynecologic cancer receiving Paclitaxel and carboplatin chemotherapy
- •Normal CBC,Liver, renal function
- •Communication in Thai language or Thai caregiver
- •Inform consent
Exclusion Criteria
- •Pregnancy
- •Active infection
- •Bowel obstruction or history of bowel surgery
- •On dopamine receptor antagonists or psychiatric or anticonvulsant medication
- •Olanzapine allery
- •Abnormal function of liver and renal
- •Diabetic melitus or morbid obesity
- •patient can't selfcare
Outcomes
Primary Outcomes
Efficacy of olanzapine on weight gain in advanzed stage gynecologic cancer recieving paclitexal and carboplatin chemotherapy
Time Frame: 12 weeks after intervention
proprotion of pateints gain weight after intervention (olanzapine or placebo) by monitor weight before and after get intervention
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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