A clinical study to evaluate the effect of Swayamguptadi Bija churna in management of Kshina Shukra(Oligospermia)
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 试验地点
- 1
研究概览
简要总结
Infertility is a growing global health problem and male infertility contributes significantly to it. Oligospermia is defined as a reduced sperm concentration and is one of the leading causes of male infertility. A large number of men worldwide are affected by infertility and in India a considerable proportion of infertile couples have male factor involvement. Low sperm count and poor sperm quality are responsible for most cases of male infertility and are influenced by lifestyle factors environmental exposure infections congenital causes and advancing age.
Although modern assisted reproductive techniques are available they are costly and impose emotional and financial stress on couples. Therefore there is a need for safe affordable and effective alternative treatment options.Ayurveda explains male infertility under conditions such as Kshina Shukra which occurs due to depletion or vitiation of Shukra Dhatu caused by imbalance of Doshas. Classical texts describe the use of Vajikarana and Rasayana therapies to improve Shukra Dhatu and reproductive health.
Swayamguptadi Bija Churna is a classical Ayurvedic formulation containing Atmagupta Ikshuraka and Sharkara which are known for their Vrishya and Brimhana properties. These drugs are believed to enhance Shukra Dhatu improve semen parameters and strengthen the male reproductive system. Avipatti Churna is used as an adjuvant to support digestion and absorption of the formulation.
However scientific clinical evidence supporting the efficacy of Swayamguptadi Bija Churna in oligospermia is limited. Hence the present study is planned to systematically evaluate the effect of Swayamguptadi Bija Churna in the management of Kshina Shukra or oligospermia using semen analysis parameters. This study aims to bridge the gap between classical Ayurvedic concepts and modern scientific validation and may provide an effective affordable and holistic treatment approach for male infertility.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 21.00 Year(s) 至 50.00 Year(s)(—)
- 性别
- Male
入选标准
- •The sperm count is less than or equal to 15 million per milliliter Willing to participate and give informed consent.
排除标准
- •K/c/o Azoospermia.
- •K/c/o Genetic disorder that could affect spermatogenesis, K/c/o Klinefelter syndrome, Kallmann’s syndrome.
- •History of Orchiectomy or Testicular trauma, Varicocele, Hydrocele.
- •Past h/o Mumps orchitis.
- •K/c/o Uncontrolled diabetes, sexually transmitted disease.
研究者
Balaje G
Sri Jayendra Saraswathi Ayurveda College and Hospital
