Ayurveda medicated oil enema and janubasti(oil pulling on knee) in knee joint pain.
- Conditions
- Osteoarthritis of knee, unspecified,
- Registration Number
- CTRI/2018/02/012163
- Lead Sponsor
- National Institute Of Ayurveda
- Brief Summary
Ø**Effect of Therapy on *Sandhishoola* (Knee Joint Pain): -**
In Group A, the meanbefore treatment was 5.286 which improved to 3.714 after treatment. It showedan improvement with Mean Difference of 1.571 ±0.7559 (S.D) with 29.72%. Thestatistical analysis showed very significant result at p value (< 0.0005).
In Group B, the meanscore before treatment was 4.867 which improved to 2.733 after treatment. Itshowed an improvement with Mean Difference of 2.133±0.5164 (S.D.) with43.82%.The statistical analysis showed extremely significant result at p value <0.0001.
Intergroup comparisonwas done to assess the comparative efficacy of both groups. When Group A wascompared with Group B on symptom of *Sandhishoola*, the two-tailed pvalue was 0.0327that was significant. it means that their statisticaldifference in the efficacy of both treatments on *Sandhishoola*.
Vitiation of *Vata* has an important role inthe arising of*Janu-Sandhigata Vata*. *Shoola*doesn’t occur without *Vata*. The *Rukshata* of *Vata* is cured by *Taila*dueto *Snigdha*. The *Virya* of *Tailla* is *Ushna*. It has effect on *VatikaShoola*. *Tilataila* has *Snehana*, *Vedanasthapana*, *Sandhaniya*, *ShoolaPrashamana*,*Balyakarma*. *Basti* is the best medicament for *Vatika* disorders. The properties of *Basti* which is *Vatanulomana*and*Srotoshodhaka*remove the impacted stool mass in the body and pacifying *Vata* in*Pakvashaya*gives direct effect on*Janu-Sandhigata Vata*.Similarly, effect of *Snehana*and *Swedana* is worth mentioning, as *Snehana* is said to be *Mardavakara*and*Swedana* is said to be *Shoolaghna.* Thus, irrespective of the materialused these two procedures will have a certain positive effect towards reducing *Shoola.*
Ø **Effect ofTherapy on *Sandhisotha* (Swelling overjoints): -**
In Group A, the mean score before treatment was1.833 which improved to 0.333 after treatment. It showed an improvement withMean Difference of 1.500 ±0.674 (S.D). with 81.83% change. The statisticalanalysis showed very significant result at p value < 0.0005.
In Group B, themean before treatment was 1.750 which improved to 0.2500 after treatment. Itshowed an improvement with Mean Difference of 1.500±0.674 (S.D.). with 85.71%change. The statistical analysis showed significant result at p value <0.0005. which 85.71% change.
Intergroupcomparison was done to assess the comparative efficacy of both groups. WhenGroup A was compared with Group B on symptom of*Sandhisotha*, the two-tailed p value was 0.7908that was insignificant.Its means there is no statistical difference in the efficacy of both treatmentson*Sandhisotha*.
The*Ushnata* applied by the *Janu Basti* procedure and *UshnaVirya* of drugs do the *Pachana* of the *Dushya* involved in the formation of *Sotha*. Due to this action the *Sotha*mighthave reduced in Group B.
Ø **Effect ofTherapy on *Sandhigraha*(Stiffness injoints): -**
InGroup A, the mean score before treatment was 2.000 which improved to 1.000after treatment. It showed an improvement with Mean Difference of 1.000 ±0.6030(S.D). with50% change. The statistical analysis showed very significant resultat p value < 0.0020.
In Group B, themean before treatment was 2.000 which improved to 0.6667 after treatment. Itshowed an improvement with Mean Difference of 1.333 ±0.4880 (S.D.). with 66.65%change. The statistical analysis showed extremely significant result at p value< 0.0001.
Intergroupcomparison was done to assess the comparative efficacy of both groups. WhenGroup A was compared with Group B on symptom of*Sandhigraha*,the two-tailed p value was 0.0459that was insignificant.
Joint stiffness is feature of *JanuSandhigataVata*which is caused by *Rooksha* and *SheetaGuna* of *Vata*.
The heat applied through the *JanuBasti*(retentionof oil on knee joint)with *ShvadanstraTaila,*retention of *Taila* and *UshnaVeerya* of *Taila* along *with* its *Snigdhata* decreases the *Rooksha* and *SheetaGuna* and reduce the stiffness.
*Janu**Basti* being successful in relieving the stiffness because ofits*Snehana*and *Swedana* effects simultaneously.Due to its *SnehanaGuna,Vata* gets pacified and *Swedana* causes relief in*Stabdhata*, *Gaurava*and*Sheeta* dueto its inherent qualities.
Ø **Effect ofTherapy on *Sandhisphutana* (Crepitus):-**
In Group A, the mean before treatment was 1.929which improved to 1.714 after treatment. It showed an improvement with MeanDifference of 0.214 ±0.4258 (S.D). with 50% change. The statistical analysisshowed insignificant result at p value < 0.2500.
In Group B, the mean beforetreatment was 1.5333 which improved to 1.333 after treatment. It showed animprovement with Mean Difference of 0.2000 ±0.4140 (S.D.). with 13.346% change.The statistical analysis showed insignificant result at p value < 0.2500.
Intergroup comparison was done to assess thecomparative efficacy of both groups. When Group A was compared with Group B onsymptom of*Sandhisphutana*, thetwo-tailed p value was 0.2500that was insignificant. Its means there is nostatistical difference in the efficacy of both treatments on*Sandhisphutana*.
**Effect of Therapy on *Sparshasahyata* (Tenderness): -**
In Group A, themean before treatment was 1.60 which improved to 0.2000 after treatment. Itshowed an improvement with Mean Difference of 1.400 ±0.547 (S.D). with 87.5%change. The statistical analysis showed insignificant result at p value <0.0625.
In Group B, themean before treatment was 1.66 which improved to 0.2000 after treatment. Itshowed an improvement with Mean Difference of 1.400 ±0.5477 (S.D.). with 87.5%change. The statistical analysis showed insignificant result at p value <0.0625.
Intergroupcomparison was done to assess the comparative efficacy of both groups. WhenGroup A was compared with Group B on symptom of*Sparshasahyata*,the two-tailed p value was 0.2154that was insignificant.Its means there is no statistical difference in theefficacy of both treatments on*Sparsaasahyata*.
Tenderness is advanced stage of pain. Skin is thelodging place for *Vata.* Thus this can be said that tenderness is felt atdifferent dermatomes when the nerve is compressed. *MatraBasti*with *ShvadanstraTaila*hasanti-inflammatory, analgesic properties, due to anti- inflammatory effects of *Shvadanstra*. It may help in reducing thecompression of nerve by reducing inflammation of articular cartilages. *Taila* soothes the joints and also helpstreating levels of synovial fluid making the entire structure lubricated andeasy to rotate or to move. *Taila*improves blood supply to joints and restores integrity of vessels obliteratedby spasm of internal damage. Thus reduction of Tenderness was seen in both thegroups.
Ø **Effect of Therapyon WOMAC Index Score: -**
In Group A, the mean beforetreatment was 55.21 which improved to 37.14 after treatment. It showed animprovement with Mean Difference of 18.071 ±8.453(S.D). with 32.729 % change.The statistical analysis showed insignificant result at p value < 0.0625.
In Group B, themean before treatment was 50.467 which improved to 29.467 after treatment. Itshowed an improvement with Mean Difference of 21.000 ±4.781 (S.D.). with41.611% change. The statistical analysis showed significant result at p value< 0.0001.
Intergroupcomparison was done to assess the comparative efficacy of both groups. WhenGroup A was compared with Group B on symptom ofWOMAC Index Score, the two-tailed p value was 0.8955 thatwas insignificant.Its means there is no statistical difference in the efficacyof both treatments on WOMAC IndexScore.
WOMAC index score includes pain, stiffness and physical function.Percentage of relief in Pain and stiffness was more in Group B than Group A, asdiscussed above. By improvement in pain and stiffness, the physical functionalso improves.
Ø **Effect ofTherapy on X-Ray: -** No anysignificant radiological changes were found after treatment in both groups. Maybe due to the short course of treatment and follow-up, changes in X-Ray werenot found.
**Knee joint rangeof movements**
· **Knee Joint Extension -**InGroup A, the mean before treatment was 11.667 which is same 11.667 aftertreatment. It showed an improvement with Mean Difference is zero. In group B SDis zero.
· **KneeJoint Flexion-** In Group A, the mean before treatmentwas 104.62 which improved to 116.15 after treatment. It showed an improvementwith Mean Difference of 11.538±5.911 (S.D.). with 9.93% change. The statisticalanalysis showed significant result at p value < 0.0001.
In Group B, the meanbefore treatment was 109.29 which improved to 119.29 aftertreatment. It showedan improvement with Mean Difference of -9.649±7.95 (S.D.). with9.643% change.The statistical analysis showed significant result at p value < 0.0006.
No any significantchanges were found on extension of knee joint after treatment in both groups.Intergroupcomparison was done to assess the comparative efficacy of both groups. WhenGroup A was compared with Group B on symptom ofrange of movements (flexion)the two-tailed p value was 0.1829& 0.2458 that was insignificant respectively right and left knee joint.Theseimprovement in range of motion might be due to the improvement in othersymptoms of the diseases such as pain, stiffness etc. Reduction in Pain,stiffness in turn might have overcome the restriction thus increasing the rangeof movements at knee joint.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 30
- 1.Patients between 30 and 60 years of age 2.Patients with the clinical features of SandhigataVata (Osteoarthritis of Knee Joint.) 3.Patients fit for Basti and Janu Basti.
- 4.Patients with radiological findings of Osteoarthritis along with clinical features.
- 1.Patients with severe form of systemic disorders 2.Pregnant women and lactating mother 3.Associated with simple or compound fractures 4.Patients unfit for Basti and Janu Basti.
- 5.Patients under gone knee replacement surgery.
- 6.Patients having chronicity more than 10 yrs.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement in Subjective and objective parameter 30 days
- Secondary Outcome Measures
Name Time Method To find the comparative efficacy of the treatments indifferent groups.
Trial Locations
- Locations (1)
National Institute of Ayurveda
🇮🇳Jaipur, RAJASTHAN, India
National Institute of Ayurveda🇮🇳Jaipur, RAJASTHAN, Indiadr jyoti bala damorPrincipal investigator9784627610jyotibaladamor1992@gmail.com