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A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease (TRIUMPH-3)

Phase 1
Recruiting
Conditions
Cardiovascular Disease, Obesity
Therapeutic area: Diseases [C] - Nutritional and Metabolic Diseases [C18]
Registration Number
CTIS2023-503659-88-00
Lead Sponsor
Eli Lilly & Co.
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
1800
Inclusion Criteria

Have obesity., Have established heart disease., Have history of unsuccessful dietary weight loss effort

Exclusion Criteria

have had the following within 90 days before screening: heart attack, stroke, a procedure to get blood flowing back into the heart, or been hospitalized for either congestive heart failure or sudden chest pain because of a blood clot in the heart, Have been taking weight loss drugs, including over-the-counter medications, within 90 days before screening, Have a self-reported change in body weight greater than 11 pounds within 90 days before screening., have undergone weight loss surgery (e.g. stomach stapling, lap banding) within 1 year before screening, Have Type 1 diabetes, Family or personal history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN-2), Have had chronic or acute pancreatitis

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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