New Score for Pseudo- Acanthosis Nigricans

Not Applicable

• Conditions: Pseudo Acanthosis Nigricans
• Interventions: Other: Saline; Procedure: Glycolic acids peel 70%

• Registration Number: NCT04359485
• Lead Sponsor: Kasr El Aini Hospital

Brief Summary

Each side of the neck pseudo acanthosis nigricans was randomized in to either receiving glycolic acid peel or saline. Evaluation was done at baseline and after 3 sessions 2 weeks apart by percentage involvement and by ANASI score

Detailed Description

Not available

Study Timeline

• Study Start: 2019-08-01
• Primary Completion: 2019-11-01
• Status Verified: 2020-04
• Study First Submitted: 2020-04-21
• Study First Submitted QC: 2020-04-22
• Last Update Submitted: 2020-04-22
• Study First Posted: 2020-04-24
• Last Update Posted: 2020-04-24
• Study Completion: 2020-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• mild to moderate severity
• age > 18 years old

Exclusion Criteria

• Pregnant and lactating patients,
• patients with systemic diseases as connective tissue disease, diabetes,
• skin infection
• use of immunosuppressive drugs
• Susceptibility for post peel hazards as hyperpigmentation
• scarring and keloidal tendency

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Saline	Saline	-
glycolic acid peel	Glycolic acids peel 70%	-

Primary Outcome Measures

Name	Time	Method
Percentage involvement	6 months to 1 year	Degree of severity expressed as a percentage
Acanthosis Nigricans Area and Severity Index score	6 months to 1 year	New Score calculating severity and area as a number minimum value is 0 and maximum value is 40 the higher the number of the score the worse the affection

Trial Locations

Locations (1)

Kasr El Ainy university hospital, Faulty of medicine,Cairo university; 🇪🇬 Cairo, Egypt