跳至主要内容
临床试验/NCT05338684
NCT05338684Unknown不适用

Role of the Radiologist in Management of Pulsatile Tinnitus

Mohab Mohammed0 个研究点目标入组 50 人开始时间: 2022年4月17日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
50
主要终点
Manage pulsatile tinnitus with catheter angiography to all vascular lesion

研究概览

简要总结

The aim of this study is to detect the role of interventional radiology in management of Pulsatile tinnitus and to detect the best imaging modality for Diagnosis.

详细描述

Tinnitus is a broad and complex subject concerning a symptom rather than a syndrome or a disease (1 ),New studies indicate that prevalence of tinnitus is 14.5% among those less than 40 years old and 17.5 - 35% among age over 40 years Old( 2-3 ). Vascular tinnitus causes are multiple , Arterial causes like Atherosclerosis , Fibromuscular dysplasia or Dissection of the carotid or vertebral artery , Arteriovenous causes like Cerebral head and neck arteriovenous malformation , Dural arteriovenous fistula and Carotid cavernous fistula Venous like Systemic diseases with hyperdynamic circulation . Chronic anemia, pregnancy, thyrotoxicosis , Idiopathic intracranial hypertension and Dural venous sinus stenosis , Tumors also like Paraganglioma which Some authors believe that para-gangliomas are the most common cause of vascular tinnitus and Vascular metastasis And other Miscellaneous Causes like Paget's disease m Otosclerosis or Otomastoiditis , but others see dural arteriovenous fistula (AVF) ,idiopathicvenous tinnitus, or idiopathic intracranial hypertension the most common causes. (4 - 9) , Also One of the Most important Arterial causes is Atherosclerosis , Atherosclerotic plaques ma produce turbulence of carotid flow and occasionally cause pulsatile tinnitus (10 ) , FMD ( Fibromuscular Dysplasia ) seen in 0.5% to0.6% of carotid angiograms and autopsies, is the second most common cause of extracranial carotid narrowing (11) information obtained from both CT and MRI is complementary In some casesThe angiographic findings may include luminal stenosis, abrupt reconstitution of the lumen, dissecting aneurysm, intimal flap, slow flow, occlusion, and distal emboli (12-15)

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • Patients with pulsatile tinnitus of unknown origin referred by a physician to diagnostic radiology to be assessed by imaging will be included in the study.
  • Patient's with clinical diagnosed pulsatile tinnitus.
  • patient refused surgical intervention.

排除标准

  • History of allergy to the contrast media , Contraindication to MRI and Refusal to sign a consent
  • Pregnant women
  • patients with atherosclerosis cause only or vascular loop more than 50% in internal auditory canal

结局指标

主要结局

Manage pulsatile tinnitus with catheter angiography to all vascular lesion

时间窗: Baseline

Manage pulsatile tinnitus causes with no indication for surgical intervention or prolonged and follow up and detect reported cases with pulsatile tinnitus could be managed by therapeutic angiography rather than other invasive surgical maneuver or Medical treatment

次要结局

  • To assess the accuracy of best imaging modality to diagnose pulsatile tinnitus .(Baseline)

研究者

发起方
Mohab Mohammed
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Mohab Mohammed

Role of the Radiologist in Management of Pulsatile tinnitus

Assiut University

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