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Clinical Trials/NCT05338684
NCT05338684UnknownNot Applicable

Role of the Radiologist in Management of Pulsatile Tinnitus

Mohab Mohammed0 sites50 target enrollmentStarted: April 17, 2022Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Sponsor
Enrollment
50
Primary Endpoint
Manage pulsatile tinnitus with catheter angiography to all vascular lesion

Study Overview

Brief Summary

The aim of this study is to detect the role of interventional radiology in management of Pulsatile tinnitus and to detect the best imaging modality for Diagnosis.

Detailed Description

Tinnitus is a broad and complex subject concerning a symptom rather than a syndrome or a disease (1 ),New studies indicate that prevalence of tinnitus is 14.5% among those less than 40 years old and 17.5 - 35% among age over 40 years Old( 2-3 ). Vascular tinnitus causes are multiple , Arterial causes like Atherosclerosis , Fibromuscular dysplasia or Dissection of the carotid or vertebral artery , Arteriovenous causes like Cerebral head and neck arteriovenous malformation , Dural arteriovenous fistula and Carotid cavernous fistula Venous like Systemic diseases with hyperdynamic circulation . Chronic anemia, pregnancy, thyrotoxicosis , Idiopathic intracranial hypertension and Dural venous sinus stenosis , Tumors also like Paraganglioma which Some authors believe that para-gangliomas are the most common cause of vascular tinnitus and Vascular metastasis And other Miscellaneous Causes like Paget's disease m Otosclerosis or Otomastoiditis , but others see dural arteriovenous fistula (AVF) ,idiopathicvenous tinnitus, or idiopathic intracranial hypertension the most common causes. (4 - 9) , Also One of the Most important Arterial causes is Atherosclerosis , Atherosclerotic plaques ma produce turbulence of carotid flow and occasionally cause pulsatile tinnitus (10 ) , FMD ( Fibromuscular Dysplasia ) seen in 0.5% to0.6% of carotid angiograms and autopsies, is the second most common cause of extracranial carotid narrowing (11) information obtained from both CT and MRI is complementary In some casesThe angiographic findings may include luminal stenosis, abrupt reconstitution of the lumen, dissecting aneurysm, intimal flap, slow flow, occlusion, and distal emboli (12-15)

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Diagnostic
Masking
None

Eligibility Criteria

Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Patients with pulsatile tinnitus of unknown origin referred by a physician to diagnostic radiology to be assessed by imaging will be included in the study.
  • Patient's with clinical diagnosed pulsatile tinnitus.
  • patient refused surgical intervention.

Exclusion Criteria

  • History of allergy to the contrast media , Contraindication to MRI and Refusal to sign a consent
  • Pregnant women
  • patients with atherosclerosis cause only or vascular loop more than 50% in internal auditory canal

Outcomes

Primary Outcomes

Manage pulsatile tinnitus with catheter angiography to all vascular lesion

Time Frame: Baseline

Manage pulsatile tinnitus causes with no indication for surgical intervention or prolonged and follow up and detect reported cases with pulsatile tinnitus could be managed by therapeutic angiography rather than other invasive surgical maneuver or Medical treatment

Secondary Outcomes

  • To assess the accuracy of best imaging modality to diagnose pulsatile tinnitus .(Baseline)

Investigators

Sponsor
Mohab Mohammed
Sponsor Class
Other
Responsible Party
Sponsor Investigator
Principal Investigator

Mohab Mohammed

Role of the Radiologist in Management of Pulsatile tinnitus

Assiut University

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