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临床试验/NCT01376440
NCT01376440已完成1 期

Acceptability and Effectiveness of Household Water Chlorination in Reducing the Prevalence of Diarrhea Among Under Five Children in Eastern Ethiopia

Haramaya Unversity2 个研究点 分布在 1 个国家目标入组 845 人开始时间: 2011年6月1日最近更新:
适应症

试验速览

阶段
1 期
状态
已完成
发起方
入组人数
845
试验地点
2
主要终点
To assess the prevalence of diarrhea among under five children

研究概览

简要总结

The Millenium development goals (MDGs) call for reducing by half the proportion of people without sustainable access to safe drinking water. This goal was adopted in large part because safe drinking water has been seen as critical to fighting diarrheal disease. Source protection is considered the main intervention area to achieve this goal. However, research worldwide that has shown that even drinking water which is safe at the source is subject to frequent and extensive fecal contamination during collection, storage and use in the home. This contamination is through the introduction of cups, dippers or hands, contamination by flies, cockroaches, and rats. Even piped water supplies of adequate microbial quality can pose infectious disease risks if they become contaminated due to unsanitary collection, storage conditions and practices within households.

To reduce this problem, point-of-use water treatment has been advocated as a means to substantially decrease the global burden of diarrhea and to contribute to the MDGs. However, research indicates that there are many unanswered questions around Household water treatment (HWT) that require small or medium scale epidemiological studies and randomized controlled trials, especially with regard to effectiveness, acceptability and identifying suitable target populations. Some of the most urgent questions to be resolved are:(1) How much of the currently cited disease reduction of HWT is due to bias? (2) What is the effect of HWT on nutritional status (weight gain and growth)?(3) At which populations should HWT be targeted? (4) Is it acceptable and sustainable in poor communities where the risk of diarrheal disease is high.

hypothesis: Do household water treatment with chlorine reduce diarrhea among underfive children? hypothesis: Do household water treatment with chlorine acceptable in the community?

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
1 Month 至 59 Months(Child)
性别
All
接受健康志愿者

入选标准

  • All children under five years of age in the randomly selected clusters of Kersa district

排除标准

  • seriously sick children in the randomly selected clusters of Kersa district

结局指标

主要结局

To assess the prevalence of diarrhea among under five children

时间窗: four months

weekly visit of the household for the presence of diarrhoea among underfive for four months in both the intervention and control groups

次要结局

  • To assess the weight gain among the intervention and control groups of under five children(At the beginning and end of the study ( 4 months interval))
  • Residual chlorine test(four months)

研究者

发起方
Haramaya Unversity
申办方类型
Other
责任方
Principal Investigator
主要研究者

Bezatu Mengiste

Mr

Haramaya Unversity

研究点 (2)

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