Definitive Selection of Neuroimaging Biomarkers for the Diagnosis and Treatment to Common Mental Disorders

Not Applicable

Completed

• Conditions: Common Mental Disorder

• Registration Number: NCT04218981

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-12-27
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Inclusion Criteria:<br><br> - Diagnostic criteria for schizophrenia,bipolar disorder, major depressive disorder<br> according to the Structural Clinical Interview for Diagnostic and Statistical Manual<br> of Mental Disorders, Fourth Edition (DSM-IV)<br><br> - Never received any treatment before.<br><br> - For healthy controls: their first-degree relative had no history of psychiatric<br> disorders.<br><br>Exclusion Criteria:<br><br> - The exclusion criteria for all subjects were as follows: any physical illnesses,<br> such as liver, kidney, and cardiovascular diseases; any current or past<br> neuropsychiatric disorders; any traumatic brain injury; seizures; serious impulsive<br> behavior; drug or alcohol addiction; contraindications for MRI; and pregnancy.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Resting-state functional magnetic resonance imaging (fMRI) data acquisition for all participants;Positive and Negative Syndrome Scale (PANSS);Hamilton Depression Scale-17 (HAMD-17);Young Mania Rating Scale (YMRS);Brief Cognitive Assessment Tool for schizophrenia(B-CATS)

Secondary Outcome Measures

Name	Time	Method
Social Disability Screening Schedule(SDSS)