Stromal Vascular Fraction Enriched PRP in Treatment of Post-acne Scars

Not Applicable

Not yet recruiting

• Conditions: Acne Scars - Atrophic
• Interventions: Biological: Stromal vascular fraction (SVF) enriched platelet rich plasma (PRP) versus each alone

• Registration Number: NCT06524011
• Lead Sponsor: Zagazig University

Brief Summary

in a split face fashion, 30 patients will be randomized into 3 groups: Group A: rt side treated with SVF enriched PRP, lt side treated with prp Group B: rt side treated with SVF enriched PRP, lt side treated with SVF Group C: rt side treated with PRP, lt side treated with SVF

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-10-06
• Status Verified: 2024-07
• Study First Submitted QC: 2024-07-24
• Last Update Submitted: 2024-07-24
• Study First Posted: 2024-07-29
• Last Update Posted: 2024-07-29
• Study Start: 2024-12
• Primary Completion: 2025-12
• Study Completion: 2026-02

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• patients with atrophic post acne scars without any previous treatment trials.
• adequate blood picture, no anemia, no bleeding or platelet disorders.

Exclusion Criteria

• pregnant and lactating females.
• elderly.
• patients with bleeding tendencies.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
SVF enriched PRP vs SVF	Stromal vascular fraction (SVF) enriched platelet rich plasma (PRP) versus each alone	-
PRP vs SVF	Stromal vascular fraction (SVF) enriched platelet rich plasma (PRP) versus each alone	-
SVF enriched PRP vs PRP	Stromal vascular fraction (SVF) enriched platelet rich plasma (PRP) versus each alone	-

Primary Outcome Measures

Name	Time	Method
change in severity of acne scars using Goodman scoring system	3 monthly sessions and follow up for 3 months after the last visit	at baseline, acne scars will be assessed clinically using the 4 point grading system proposed by Goodman \&colleagues in 2006, patients' complaints and expectations will be addressed as well and the impact of acne scars on patients' quality of life will be investigated using the dermatology life quality index (DLQI). Goodman scoring system will be used at the last session and at the follow up visit to measure the change pre and post treatment.

Trial Locations

Locations (1)

Zagazig University Hospitals; 🇪🇬 Zagazig, Egypt